Anke Konrad
Overview
Explore the profile of Anke Konrad including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
301
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Recent Articles
1.
Katju V, Konrad A, Deiss T, Bergthorsson U
G3 (Bethesda)
. 2021 Dec;
12(1).
PMID: 34849777
DNA mismatch repair (MMR), an evolutionarily conserved repair pathway shared by prokaryotic and eukaryotic species alike, influences molecular evolution by detecting and correcting mismatches, thereby protecting genetic fidelity, reducing the...
2.
Bergthorsson U, Sheeba C, Konrad A, Belicard T, Beltran T, Katju V, et al.
BMC Biol
. 2020 Nov;
18(1):162.
PMID: 33158445
Background: Transposable elements (TEs) are an almost universal constituent of eukaryotic genomes. In animals, Piwi-interacting small RNAs (piRNAs) and repressive chromatin often play crucial roles in preventing TE transcription and...
3.
Barreto H, Frazao N, Sousa A, Konrad A, Gordo I
Commun Integr Biol
. 2020 Oct;
13(1):89-96.
PMID: 33014261
The ecology and environment of the microbes that inhabit the mammalian intestine undergoes several changes as the host ages. Here, we ask if the selection pressure experienced by a new...
4.
Konrad A, Brady M, Bergthorsson U, Katju V
Genetics
. 2019 May;
212(3):837-854.
PMID: 31110155
Experimental investigations into the rates and fitness effects of spontaneous mutations are fundamental to our understanding of the evolutionary process. To gain insights into the molecular and fitness consequences of...
5.
Konrad A, Flibotte S, Taylor J, Waterston R, Moerman D, Bergthorsson U, et al.
Proc Natl Acad Sci U S A
. 2018 Jun;
115(28):7386-7391.
PMID: 29941601
Gene duplication and deletion are pivotal processes shaping the structural and functional repertoire of genomes, with implications for disease, adaptation, and evolution. We employed a mutation accumulation (MA) framework partnered...
6.
Konrad A, Thompson O, Waterston R, Moerman D, Keightley P, Bergthorsson U, et al.
Mol Biol Evol
. 2017 Jan;
34(6):1319-1334.
PMID: 28087770
Mitochondrial genomes of metazoans, given their elevated rates of evolution, have served as pivotal markers for phylogeographic studies and recent phylogenetic events. In order to determine the dynamics of spontaneous...
7.
Konrad A, Lai J, Mutahir Z, Piskur J, Liberles D
J Mol Evol
. 2014 Feb;
78(3-4):202-16.
PMID: 24500774
Deoxyribonucleoside kinases (dNKs) carry out the rate-determining step in the nucleoside salvage pathway within all domains of life where the pathway is present, and, hence, are an indication on whether...
8.
Konrad A, Piskur J, Liberles D
Gene
. 2012 Sep;
510(2):154-61.
PMID: 22967797
Nucleoside phosphorylases are essential for the salvage and catabolism of nucleotides in bacteria and other organisms, and members of this enzyme superfamily have been of interest for the development of...
9.
Tinta T, Christiansen L, Konrad A, Liberles D, Turk V, Munch-Petersen B, et al.
FEMS Microbiol Lett
. 2012 Apr;
331(2):120-7.
PMID: 22462611
Deoxyribonucleoside kinases (dNKs) are essential in the mammalian cell but their 'importance' in bacteria, especially aquatic ones, is less clear. We studied two aquatic bacteria, Gram-negative Flavobacterium psychrophilum JIP02/86 and...
10.
Konrad A, Yarunova E, Tinta T, Piskur J, Liberles D
Gene
. 2011 Nov;
492(1):117-20.
PMID: 22057012
Deoxyribonucleoside kinases (dNKs) are important to DNA metabolism, especially in environments where nucleosides are freely available to be absorbed and used for the salvage pathway. Little has previously been known...