Robert H Waterston
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Explore the profile of Robert H Waterston including associated specialties, affiliations and a list of published articles.
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78
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11171
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Recent Articles
1.
Waterston R
Annu Rev Genomics Hum Genet
. 2025 Jan;
PMID: 39879557
In this short memoir, I recount the series of improbable interactions and events that led me from medical school to a leadership role in the Human Genome Project.
2.
Kudron M, Gevirtzman L, Victorsen A, Lear B, Gao J, Xu J, et al.
Genome Res
. 2024 Oct;
34(12):2319-2334.
PMID: 39438113
A catalog of transcription factor (TF) binding sites in the genome is critical for deciphering regulatory relationships. Here, we present the culmination of the efforts of the modENCODE (model organism...
3.
Kudron M, Gevirtzman L, Victorsen A, Lear B, Gao J, Xu J, et al.
bioRxiv
. 2024 Jan;
PMID: 38293065
A catalog of transcription factor (TF) binding sites in the genome is critical for deciphering regulatory relationships. Here we present the culmination of the modERN (model organism Encyclopedia of Regulatory...
4.
Fisher W, Hammonds A, Weiszmann R, Booth B, Gevirtzman L, Patton J, et al.
Genetics
. 2023 Jan;
223(4).
PMID: 36652461
Transcription factors (TFs) play a key role in development and in cellular responses to the environment by activating or repressing the transcription of target genes in precise spatial and temporal...
5.
Durham T, Daza R, Gevirtzman L, Cusanovich D, Bolonduro O, Noble W, et al.
Genome Res
. 2021 Apr;
31(10):1952-1969.
PMID: 33888511
Recently developed single-cell technologies allow researchers to characterize cell states at ever greater resolution and scale. is a particularly tractable system for studying development, and recent single-cell RNA-seq studies characterized...
6.
Waterston R, Moerman D
J Neurogenet
. 2021 Jan;
34(3-4):238-246.
PMID: 33446017
John Sulston changed the way we do science, not once, but three times - initially with the complete cell lineage of the nematode , next with completion of the genome...
7.
Xu J, Kudron M, Victorsen A, Gao J, Ammouri H, Navarro F, et al.
Nucleic Acids Res
. 2020 Dec;
49(3):e17.
PMID: 33347581
Chromatin immunoprecipitation (IP) followed by sequencing (ChIP-seq) is the gold standard to detect transcription-factor (TF) binding sites in the genome. Its success depends on appropriate controls removing systematic biases. The...
8.
Mok C, Belmarez G, Edgley M, Moerman D, Waterston R
G3 (Bethesda)
. 2020 Sep;
10(11):3977-3990.
PMID: 32868407
Whether generated within a lab setting or isolated from the wild, variant alleles continue to be an important resource for decoding gene function in model organisms such as With advances...
9.
Parkinson J, Mitreva M, Whitton C, Thomson M, Daub J, Martin J, et al.
Nat Genet
. 2020 Jun;
52(7):750.
PMID: 32541926
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
Packer J, Zhu Q, Huynh C, Sivaramakrishnan P, Preston E, Dueck H, et al.
Science
. 2019 Sep;
365(6459).
PMID: 31488706
is an animal with few cells but a wide diversity of cell types. In this study, we characterize the molecular basis for their specification by profiling the transcriptomes of 86,024...