Anke Jeschke
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Explore the profile of Anke Jeschke including associated specialties, affiliations and a list of published articles.
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29
Citations
479
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Recent Articles
1.
Trabszo C, Ramms B, Chopra P, Lullmann-Rauch R, Stroobants S, Spross J, et al.
Biochem J
. 2020 Aug;
477(17):3433-3451.
PMID: 32856704
Mucopolysaccharidoses comprise a group of rare metabolic diseases, in which the lysosomal degradation of glycosaminoglycans (GAGs) is impaired due to genetically inherited defects of lysosomal enzymes involved in GAG catabolism....
2.
Bonitz M, Schaffer C, Amling M, Poertner R, Schinke T, Jeschke A
Gene
. 2019 Mar;
698:1-8.
PMID: 30825594
Although articular cartilage degeneration in osteoarthritis represents a major public health problem, there is still no molecular approach to prevent this pathology by blocking specific molecules. We have previously applied...
3.
Schmidt T, Schwinge D, Rolvien T, Jeschke A, Schmidt C, Neven M, et al.
J Hepatol
. 2019 Jan;
70(5):941-953.
PMID: 30641095
Background & Aims: Osteoporotic fractures are a major cause of morbidity and reduced quality of life in patients with primary sclerosing cholangitis (PSC), a progressive bile duct disease of unknown...
4.
Pohl S, Angermann A, Jeschke A, Hendrickx G, Yorgan T, Makrypidi-Fraune G, et al.
J Bone Miner Res
. 2018 Aug;
33(12):2186-2201.
PMID: 30075049
Skeletal pathologies are frequently observed in lysosomal storage disorders, yet the relevance of specific lysosomal enzymes in bone remodeling cell types is poorly defined. Two lysosomal enzymes, ie, cathepsin K...
5.
Rolvien T, Schmidt F, Milovanovic P, Jahn K, Riedel C, Butscheidt S, et al.
Sci Rep
. 2018 Feb;
8(1):1920.
PMID: 29382878
Within the mineralized bone, osteocytes form a multifunctional mechanosensitive network orchestrating bone remodelling. A preserved osteocyte population is a crucial determinant of bone quality. In human auditory ossicles, the early...
6.
Bissinger O, Gotz C, Jeschke A, Haller B, Wolff K, Kaiser P, et al.
Oral Surg Oral Med Oral Pathol Oral Radiol
. 2017 Oct;
125(1):20-26.
PMID: 29079369
Objectives: Histology is still regarded as the gold-standard to determine bone implant contact (BIC) as a parameter representing implant stability. As the further processing of cut slices for contact radiography...
7.
Vollersen N, Hermans-Borgmeyer I, Cornils K, Fehse B, Rolvien T, Triviai I, et al.
J Bone Miner Res
. 2017 Sep;
33(1):70-83.
PMID: 28856714
Hajdu-Cheney syndrome (HCS) is a rare autosomal-dominant disorder primarily characterized by acro-osteolysis and early-onset osteoporosis. Genetically, HCS is caused by nonsense or deletion mutations within exon 34 of the NOTCH2...
8.
Rolvien T, Butscheidt S, Jeschke A, Neu A, Denecke J, Kubisch C, et al.
Bone
. 2017 Jul;
103:136-143.
PMID: 28676440
Mutations in the SCN8A gene encoding the neuronal voltage-gated sodium channel Nav1.6 are known to be associated with epileptic encephalopathy type 13. We identified a novel de novo SCN8A mutation...
9.
Rolvien T, Krause M, Jeschke A, Yorgan T, Puschel K, Schinke T, et al.
Bone
. 2017 Jul;
103:78-87.
PMID: 28666969
Osteocytes are the most abundant bone cells and are highly regulated by external stimuli. Vitamin D and osteocytes cooperatively regulate bone remodeling as well as phosphate and calcium homeostasis. However,...
10.
Bartelt A, Jeschke A, Muller B, Gaziano I, Morales M, Yorgan T, et al.
PLoS One
. 2017 Jul;
12(6):e0180547.
PMID: 28666011
Key metabolic hormones, such as insulin, leptin, and adiponectin, have been studied extensively in obesity, however the pathophysiologic relevance of the calcitonin family of peptides remains unclear. This family includes...