Anka G Ehrhardt
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Explore the profile of Anka G Ehrhardt including associated specialties, affiliations and a list of published articles.
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9
Citations
280
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Recent Articles
1.
Rodrigues F, Owen G, Sathe S, Pak E, Kaur D, Ehrhardt A, et al.
J Huntingtons Dis
. 2022 Mar;
11(1):59-69.
PMID: 35253773
Background: Biomarkers are needed to monitor disease progression, target engagement and efficacy in Huntington's disease (HD). Cerebrospinal fluid (CSF) is an ideal medium to research such biomarkers due to its...
2.
Lee H, Sun Y, Patti-Diaz L, Hedrick M, Ehrhardt A
Bioinform Biol Insights
. 2019 Apr;
13:1177932219838851.
PMID: 30983860
Advancements in flow cytometers with capability to measure 15 or more parameters have enabled us to characterize cell populations at unprecedented levels of detail. Beyond discovery research, there is now...
3.
Sun Y, Yang K, Bridal T, Ehrhardt A
Bioanalysis
. 2016 Nov;
8(23):2399-2413.
PMID: 27807982
Aim: Ki67 is a prognostic and/or predictive biomarker in patients with malignancies. Flow cytometry is a powerful technology for single-cell multiparameter analysis. Results: We developed and validated a multicolor quantitative...
4.
Han S, LeVoci L, Fischer P, Wang S, Gagen K, Chen Y, et al.
Biochim Biophys Acta
. 2012 Dec;
1831(4):825-33.
PMID: 23269286
Cholesteryl ester transfer protein (CETP) is a target of therapeutic intervention for coronary heart disease. Anacetrapib, a potent inhibitor of CETP, has been shown to reduce LDL-cholesterol by 40% and...
5.
Utilizing HaloTag Technology to Track the Fate of PCSK9 from Intracellular vs. Extracellular Sources
Ai X, Fischer P, Palyha O, Wisniewski D, Hubbard B, Akinsanya K, et al.
Curr Chem Genomics
. 2012 Nov;
6:38-47.
PMID: 23115612
The function of a particular protein is dependent upon its localization and milieu. The ability to track the "fate" of a protein is a valuable tool to elucidate its function....
6.
Harvey C, Ehrhardt A, Cellurale C, Zhong H, Yasuda R, Davis R, et al.
Proc Natl Acad Sci U S A
. 2008 Nov;
105(49):19264-9.
PMID: 19033456
The activity of the ERK has complex spatial and temporal dynamics that are important for the specificity of downstream effects. However, current biochemical techniques do not allow for the measurement...
7.
Kennedy N, Martin G, Ehrhardt A, Cavanagh-Kyros J, Kuan C, Rakic P, et al.
Genes Dev
. 2007 Sep;
21(18):2336-46.
PMID: 17875667
JIP scaffold proteins are implicated in the regulation of protein kinase signal transduction pathways. To test the physiological role of these scaffold proteins, we examined the phenotype of compound mutant...
8.
Takizawa N, Smith T, Nebl T, Crowley J, Palmieri S, Lifshitz L, et al.
J Cell Biol
. 2006 Aug;
174(3):447-58.
PMID: 16880273
Cell-substrate contacts, called focal adhesions (FAs), are dynamic in rapidly moving cells. We show that supervillin (SV)--a peripheral membrane protein that binds myosin II and F-actin in such cells--negatively regulates...
9.
Ehrhardt A, Sluder G
J Cell Physiol
. 2005 Apr;
204(3):808-18.
PMID: 15828030
During interphase, the centrosome concentrates cell stress response molecules, including chaperones and proteasomes, into a proteolytic center. However, whether the centrosome functions as proteolytic center during mitosis is not known....