Anja Scheufen
Overview
Explore the profile of Anja Scheufen including associated specialties, affiliations and a list of published articles.
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8
Citations
74
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Recent Articles
1.
Juhlen R, Wiesmann S, Scheufen A, Stausberg T, Braun I, Strobel C, et al.
Nat Commun
. 2025 Mar;
16(1):2434.
PMID: 40069174
During mitosis, chromosomes condense and decondense to segregate faithfully and undamaged. The exact molecular mechanisms are not well understood. We identify the DEAD-box helicase eIF4A1/2 as a critical factor in...
2.
Scheufen A, Moreno-Andres D
Methods Mol Biol
. 2024 Nov;
2874:47-60.
PMID: 39614046
Live-cell imaging is a powerful tool for the investigation of different steps of the life and fate of single cells and cell populations. In this chapter, we describe how to...
3.
Holl K, Chatain N, Krapp S, Baumeister J, Maie T, Schmitz S, et al.
Sci Rep
. 2024 Feb;
14(1):2810.
PMID: 38308077
Myeloproliferative neoplasms (MPNs) encompass a diverse group of hematologic disorders driven by mutations in JAK2, CALR, or MPL. The prevailing working model explaining how these driver mutations induce different disease...
4.
Moreno-Andres D, Bhattacharyya A, Scheufen A, Stegmaier J
PLoS One
. 2022 Jul;
17(7):e0270923.
PMID: 35797385
Live-cell imaging has become state of the art to accurately identify the nature of mitotic and cell cycle defects. Low- and high-throughput microscopy setups have yield huge data amounts of...
5.
Holzer G, De Magistris P, Gramminger C, Sachdev R, Magalska A, Schooley A, et al.
EMBO J
. 2021 Nov;
40(23):e108788.
PMID: 34725842
During mitotic exit, thousands of nuclear pore complexes (NPCs) assemble concomitant with the nuclear envelope to build a transport-competent nucleus. Here, we show that Nup50 plays a crucial role in...
6.
Rajendiran A, Klemm P, Schippers A, Scheufen A, Schwarz T, Peitz J, et al.
Rheumatology (Oxford)
. 2021 Sep;
61(6):2694-2703.
PMID: 34559194
Objective: JIA is a chronic inflammatory disease of unknown origin. The regulation of inflammatory processes involves multiple cellular steps including mRNA transcription and translation. Different miRNAs control these processes tightly....
7.
Moreno-Andres D, Yokoyama H, Scheufen A, Holzer G, Lue H, Schellhaus A, et al.
Cells
. 2020 Jul;
9(7).
PMID: 32708675
The eukaryotic nucleus remodels extensively during mitosis. Upon mitotic entry, the nuclear envelope breaks down and chromosomes condense into rod-shaped bodies, which are captured by the spindle apparatus and segregated...
8.
Ohl K, Nickel H, Moncrieffe H, Klemm P, Scheufen A, Foll D, et al.
Pediatr Rheumatol Online J
. 2018 Jun;
16(1):39.
PMID: 29925386
Background: Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)α...
9.
Butepage M, Preisinger C, von Kriegsheim A, Scheufen A, Lausberg E, Li J, et al.
Sci Rep
. 2018 May;
8(1):6748.
PMID: 29712969
Macrodomains are conserved protein folds associated with ADP-ribose binding and turnover. ADP-ribosylation is a posttranslational modification catalyzed primarily by ARTD (aka PARP) enzymes in cells. ARTDs transfer either single or...