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Anja M van der Laan

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Articles 36
Citations 1880
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Recent Articles
1.
DeBerge M, Glinton K, Lantz C, Ge Z, Sullivan D, Patil S, et al.
Nat Cardiovasc Res . 2025 Jan; 4(1):83-101. PMID: 39747455
Myocardial infarction (MI) mobilizes macrophages, the central protagonists of tissue repair in the infarcted heart. Although necessary for repair, macrophages also contribute to adverse remodeling and progression to heart failure....
2.
Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee I, et al.
Nat Cardiovasc Res . 2024 Feb; 2(12):1277-1290. PMID: 38344689
After myocardial infarction (MI), emergency hematopoiesis produces inflammatory myeloid cells that accelerate atherosclerosis and promote heart failure. Since the balance between glycolysis and mitochondrial metabolism regulates hematopoietic stem cell homeostasis,...
3.
Hopman L, van Pouderoijen N, Mulder M, van der Laan A, Bhagirath P, Nazarian S, et al.
JACC Clin Electrophysiol . 2023 Sep; 9(12):2665-2679. PMID: 37737780
Cardiac magnetic resonance (CMR) imaging is a valuable noninvasive tool for evaluating tissue response following catheter ablation of atrial tissue. This review provides an overview of the contemporary CMR strategies...
4.
Hopman L, Bhagirath P, Mulder M, Demirkiran A, El Mathari S, van der Laan A, et al.
Int J Cardiovasc Imaging . 2023 Jul; 39(9):1753-1763. PMID: 37515682
Purpose: Left atrial (LA) sphericity is a novel, geometry-based parameter that has been used to visualize and quantify LA geometrical remodeling in patients with atrial fibrillation (AF). This study examined...
5.
Hopman L, Mulder M, van der Laan A, Bhagirath P, Demirkiran A, von Bartheld M, et al.
Int J Cardiol . 2023 Feb; 378:23-31. PMID: 36804765
Purpose: The present study assesses different left atrial (LA) strain approaches in relation to atrial fibrillation (AF) recurrence after ablation and compares LA feature tracking (FT) strain to novel rapid...
6.
Hopman L, Visch J, Bhagirath P, van der Laan A, Mulder M, Razeghi O, et al.
Eur Heart J Cardiovasc Imaging . 2022 Aug; 24(3):336-345. PMID: 35921538
Aims: Bi-atrial remodelling in patients with atrial fibrillation (AF) is rarely assessed and data on the presence of right atrial (RA) fibrosis, the relationship between RA and left atrial (LA)...
7.
Rohde D, Vandoorne K, Lee I, Grune J, Zhang S, McAlpine C, et al.
Nat Cardiovasc Res . 2022 Jun; 1(1):28-44. PMID: 35747128
Abnormal hematopoiesis advances cardiovascular disease by generating excess inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche regulates hematopoietic stem cell proliferation and hence the systemic...
8.
Hopman L, Mulder M, van der Laan A, Demirkiran A, Bhagirath P, van Rossum A, et al.
J Cardiovasc Magn Reson . 2021 Nov; 23(1):131. PMID: 34758820
Background: Atrial fibrillation (AF) is associated with profound structural and functional changes in the atria. In the present study, we investigated the association between left atrial (LA) phasic function and...
9.
DeBerge M, Lantz C, Dehn S, Sullivan D, van der Laan A, Niessen H, et al.
J Exp Med . 2021 Jul; 218(9). PMID: 34325467
Hypoxia-inducible factors (HIFs) are activated in parenchymal cells in response to low oxygen and as such have been proposed as therapeutic targets during hypoxic insult, including myocardial infarction (MI). HIFs...
10.
Chan C, Fenn A, Harder N, Mindur J, McAlpine C, Patel J, et al.
J Exp Med . 2020 Jul; 217(10). PMID: 32716519
The thymus is a primary lymphoid organ necessary for optimal T cell development. Here, we show that liver X receptors (LXRs)-a class of nuclear receptors and transcription factors with diverse...