Anja Krones-Herzig
Overview
Explore the profile of Anja Krones-Herzig including associated specialties, affiliations and a list of published articles.
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19
Citations
625
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Recent Articles
1.
Ekim Ustunel B, Friedrich K, Maida A, Wang X, Krones-Herzig A, Seibert O, et al.
Nat Commun
. 2016 Nov;
7:13267.
PMID: 27827363
Obesity-related insulin resistance represents the core component of the metabolic syndrome, promoting glucose intolerance, pancreatic beta cell failure and type 2 diabetes. Efficient and safe insulin sensitization and glucose control...
2.
de Guia R, Rose A, Sommerfeld A, Seibert O, Strzoda D, Zota A, et al.
EMBO J
. 2014 Dec;
34(3):344-60.
PMID: 25510864
In mammals, glucocorticoids (GCs) and their intracellular receptor, the glucocorticoid receptor (GR), represent critical checkpoints in the endocrine control of energy homeostasis. Indeed, aberrant GC action is linked to severe...
3.
Mattijssen F, Georgiadi A, Andasarie T, Szalowska E, Zota A, Krones-Herzig A, et al.
J Biol Chem
. 2014 May;
289(28):19279-93.
PMID: 24876382
Peroxisome proliferator-activated receptors (PPARs) play major roles in the regulation of hepatic lipid metabolism through the control of numerous genes involved in processes such as lipid uptake and fatty acid...
4.
Lutzner N, Kalbacher H, Krones-Herzig A, Rosl F
PLoS One
. 2012 Aug;
7(7):e42166.
PMID: 22848740
FOXO3 is a transcription factor involved in the regulation of multiple physiological processes including cell cycle arrest, apoptosis, oxidative stress-response and energy metabolism. Although much is known about its post-translational...
5.
Rose A, Diaz M, Reimann A, Klement J, Walcher T, Krones-Herzig A, et al.
Cell Metab
. 2011 Jul;
14(1):123-30.
PMID: 21723510
Systemic bile acid (BA) homeostasis is a critical determinant of dietary fat digestion, enterohepatic function, and postprandial thermogenesis. However, major checkpoints for the dynamics and the molecular regulation of BA...
6.
Sommerfeld A, Krones-Herzig A, Herzig S
Mol Cell Endocrinol
. 2010 Nov;
332(1-2):21-31.
PMID: 21112373
After binding to their cognate DNA-binding partner, transcriptional co-factors exert their function through the recruitment of enzymatic, chromatin-modifying activities. In turn, the assembly of co-factor-associated multi-protein complexes efficiently impacts target...
7.
Narvekar P, Diaz M, Krones-Herzig A, Hardeland U, Strzoda D, Stohr S, et al.
Diabetes
. 2009 Feb;
58(5):1040-9.
PMID: 19188430
Objective: In mammals, proper storage and distribution of lipids in and between tissues is essential for the maintenance of energy homeostasis. In contrast, aberrantly high levels of triglycerides in the...
8.
Lemke U, Krones-Herzig A, Diaz M, Narvekar P, Ziegler A, Vegiopoulos A, et al.
Cell Metab
. 2008 Sep;
8(3):212-23.
PMID: 18762022
Aberrant accumulation of lipids in the liver ("fatty liver" or hepatic steatosis) represents a hallmark of the metabolic syndrome and is tightly associated with obesity, type II diabetes, starvation, or...
9.
Diaz M, Krones-Herzig A, Metzger D, Ziegler A, Vegiopoulos A, Klingenspor M, et al.
Hepatology
. 2008 Aug;
48(3):782-91.
PMID: 18712775
Unlabelled: In mammals, triglycerides (TG) represent the most concentrated form of energy. Aberrant TG storage and availability are intimately linked to the negative energy balance under severe clinical conditions, such...
10.
Zschiedrich I, Hardeland U, Krones-Herzig A, Diaz M, Vegiopoulos A, Muggenburg J, et al.
Blood
. 2008 May;
112(2):264-76.
PMID: 18469200
Inflammatory responses represent a hallmark of numerous pathologies including sepsis, bacterial infection, insulin resistance, and malign obesity. Here we describe an unexpected coactivator function for the nuclear receptor interacting protein...