Anita B Hjelmeland
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Explore the profile of Anita B Hjelmeland including associated specialties, affiliations and a list of published articles.
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8933
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Recent Articles
11.
Gc S, Bellis S, Hjelmeland A
Front Mol Biosci
. 2022 Sep;
9:962908.
PMID: 36106023
The Golgi-sialyltransferase ST6Gal1 (βgalactosidase α2,6 sialyltransferase 1), adds the negatively charged sugar, sialic acid, to the terminal galactose of N-glycosylated proteins. Upregulation of ST6Gal1 is observed in many malignancies, and...
12.
Stackhouse C, Anderson J, Yue Z, Nguyen T, Eustace N, Langford C, et al.
JCI Insight
. 2022 Jul;
7(16).
PMID: 35852875
Key molecular regulators of acquired radiation resistance in recurrent glioblastoma (GBM) are largely unknown, with a dearth of accurate preclinical models. To address this, we generated 8 GBM patient-derived xenograft...
13.
Hawkins C, Jones A, Gordon E, Williford S, Harsh Y, Ziebro J, et al.
Cells
. 2022 Jun;
11(12).
PMID: 35741006
Glioblastoma (GBM) remains one of the most aggressive cancers, partially due to its ability to migrate into the surrounding brain. The sphingolipid balance, or the balance between ceramides and sphingosine-1-phosphate,...
14.
Jones A, Rocco A, Lamb L, Friedman G, Hjelmeland A
Cancers (Basel)
. 2022 May;
14(9).
PMID: 35565467
Under cellular distress, multiple facets of normal homeostatic signaling are altered or disrupted. In the context of the immune landscape, external and internal stressors normally promote the expression of natural...
15.
Marayati R, Julson J, Bownes L, Quinn C, Hutchins S, Williams A, et al.
J Pediatr Surg
. 2022 Mar;
57(6):1018-1025.
PMID: 35300860
Background/purpose: Metastatic hepatoblastoma continues to pose a significant treatment challenge, primarily because the precise mechanisms involved in metastasis are not fully understood, making cell lines and preclinical models that depict...
16.
Tuy K, Rickenbacker L, Hjelmeland A
Redox Biol
. 2021 May;
44:101953.
PMID: 34052208
Controlling reactive oxygen species (ROS) at sustainable levels can drive multiple facets of tumor biology, including within the cancer stem cell (CSC) population. Tight regulation of ROS is one key...
17.
Williford S, Libby C, Ayokanmbi A, Otamias A, Gordillo J, Gordon E, et al.
PLoS One
. 2021 May;
16(5):e0250649.
PMID: 33945569
Treatment for the lethal primary adult brain tumor glioblastoma (GBM) includes the chemotherapy temozolomide (TMZ), but TMZ resistance is common and correlates with promoter methylation of the DNA repair enzyme...
18.
Libby C, Gc S, Benavides G, Fisher J, Williford S, Zhang S, et al.
Cell Adh Migr
. 2021 Apr;
15(1):101-115.
PMID: 33843470
The multifaceted roles of metabolism in invasion have been investigated across many cancers. The brain tumor glioblastoma (GBM) is a highly invasive and metabolically plastic tumor with an inevitable recurrence....
19.
Boyd N, Tran A, Bernstock J, Etminan T, Jones A, Gillespie G, et al.
Theranostics
. 2021 Jan;
11(2):665-683.
PMID: 33391498
Tumor microenvironments are the result of cellular alterations in cancer that support unrestricted growth and proliferation and result in further modifications in cell behavior, which are critical for tumor progression....
20.
Eustace N, Anderson J, Warram J, Widden H, Pedersen R, Alrefai H, et al.
Oncogene
. 2020 Oct;
39(46):6961-6974.
PMID: 33077834
Glioblastoma (GBM) is an aggressive malignancy with limited effectiveness of standard of care therapies including surgery, radiation, and temozolomide chemotherapy necessitating novel therapeutics. Unfortunately, GBMs also harbor several signaling alterations...