Angelika Grudzinska
Overview
Explore the profile of Angelika Grudzinska including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
24
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0
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Recent Articles
1.
Wrobel T, Grudzinska A, Yakubu J, du Toit T, Sharma K, Harrington J, et al.
J Enzyme Inhib Med Chem
. 2025 Feb;
40(1):2463014.
PMID: 39950830
Prostate cancer (PCa) is one of the most prevalent malignancies affecting men worldwide, and androgen deprivation therapy (ADT) is a primary treatment approach. CYP17A1 inhibitors like abiraterone target the steroidogenic...
2.
Wrobel T, Jorgensen F, Pandey A, Grudzinska A, Sharma K, Yakubu J, et al.
J Med Chem
. 2023 May;
66(10):6542-6566.
PMID: 37191389
CYP17A1 is an enzyme that plays a major role in steroidogenesis and is critically involved in the biosynthesis of steroid hormones. Therefore, it remains an attractive target in several serious...
3.
Kaczor A, Kedzierska E, Wrobel T, Grudzinska A, Pawlak A, Laitinen T, et al.
Molecules
. 2023 Jan;
28(1).
PMID: 36615578
Serotonin receptors are involved in a number of physiological functions and regulate aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation. Here we report synthesis and detailed structural...
4.
Koszla O, Stepnicki P, Zieba A, Grudzinska A, Matosiuk D, Kaczor A
Biomolecules
. 2021 Jul;
11(6).
PMID: 34208760
Parkinson's disease is a progressive neurodegenerative disorder characterized by the death of nerve cells in the substantia nigra of the brain. The treatment options for this disease are very limited...
5.
Kaczor A, Targowska-Duda K, Stepnicki P, Silva A, Koszla O, Kedzierska E, et al.
Neurochem Int
. 2021 Mar;
146:105016.
PMID: 33722679
Schizophrenia is a mental illness of not adequately understood causes that is not satisfactorily enough treated by current antipsychotics. In search for novel potential antipsychotics we performed structure-based virtual screening...