Angela Boshnakovska
Overview
Explore the profile of Angela Boshnakovska including associated specialties, affiliations and a list of published articles.
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10
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14
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Recent Articles
1.
Valenti R, David Y, Edilbi D, Dubreuil B, Boshnakovska A, Asraf Y, et al.
J Cell Biol
. 2024 Dec;
224(2).
PMID: 39692734
Genome-wide collections of yeast strains, known as libraries, revolutionized the way systematic studies are carried out. Specifically, libraries that involve a cellular perturbation, such as the deletion collection, have facilitated...
2.
Shumanska M, Lodygin D, Gibhardt C, Ickes C, Stejerean-Todoran I, Krause L, et al.
EMBO Rep
. 2024 Dec;
26(2):407-442.
PMID: 39623165
T-cell receptor (TCR)-induced Ca signals are essential for T-cell activation and function. In this context, mitochondria play an important role and take up Ca to support elevated bioenergetic demands. However,...
3.
Foo B, Amedei H, Kaur S, Jaawan S, Boshnakovska A, Gall T, et al.
PLoS One
. 2024 Oct;
19(10):e0311203.
PMID: 39446877
Phospholamban (PLN) is a sarco-endoplasmic reticulum (SER) membrane protein that regulates cardiac contraction/relaxation by reversibly inhibiting the SERCA2a Ca2+-reuptake pump. The R14Δ-PLN mutation causes severe cardiomyopathy that is resistant to...
4.
Aich A, Boshnakovska A, Witte S, Gall T, Unthan-Fechner K, Yousefi R, et al.
Nat Commun
. 2024 Aug;
15(1):6914.
PMID: 39134548
Mitochondrial oxidative phosphorylation (OXPHOS) fuels cellular ATP demands. OXPHOS defects lead to severe human disorders with unexplained tissue specific pathologies. Mitochondrial gene expression is essential for OXPHOS biogenesis since core...
5.
Schneider C, Hilbert J, Genevaux F, Hofer S, Krauss L, Schicktanz F, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(31):e2307695.
PMID: 38885414
Cancer cells must develop strategies to adapt to the dynamically changing stresses caused by intrinsic or extrinsic processes, or therapeutic agents. Metabolic adaptability is crucial to mitigate such challenges. Considering...
6.
Zung N, Aravindan N, Boshnakovska A, Valenti R, Preminger N, Jonas F, et al.
bioRxiv
. 2024 May;
PMID: 38766039
Contact-sites are specialized zones of proximity between two organelles, essential for organelle communication and coordination. The formation of contacts between the Endoplasmic Reticulum (ER), and other organelles, relies on a...
7.
Prokakis E, Bamahmoud H, Jansari S, Fritsche L, Dietz A, Boshnakovska A, et al.
Cell Commun Signal
. 2024 Feb;
22(1):120.
PMID: 38347585
Background: Breast cancer (BC) is the most frequent tumor entity in women worldwide with a high chance of therapeutic response in early- and non-metastatic disease stages. Among all BC subtypes,...
8.
Prokakis E, Jansari S, Boshnakovska A, Wiese M, Kusch K, Kramm C, et al.
Cell Death Dis
. 2023 Sep;
14(9):641.
PMID: 37770435
Triple-negative breast cancer (TNBC) is the most difficult breast cancer subtype to treat due to the lack of targeted therapies. Cancer stem cells (CSCs) are strongly enriched in TNBC lesions...
9.
Chowdhury A, Boshnakovska A, Aich A, Methi A, Vergel Leon A, Silbern I, et al.
EMBO Mol Med
. 2023 Aug;
15(9):e17399.
PMID: 37533404
Mitochondria are central for cellular metabolism and energy supply. Barth syndrome (BTHS) is a severe disorder, due to dysfunction of the mitochondrial cardiolipin acyl transferase tafazzin. Altered cardiolipin remodeling affects...
10.
Witte S, Boshnakovska A, Ozdemir M, Chowdhury A, Rehling P, Aich A
Biol Open
. 2023 Mar;
12(3).
PMID: 36861685
Mitochondrial defects are associated with aging processes and age-related diseases, including cardiovascular diseases, neurodegenerative diseases and cancer. In addition, some recent studies suggest mild mitochondrial dysfunctions appear to be associated...