Andrzej W Cwetsch
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Explore the profile of Andrzej W Cwetsch including associated specialties, affiliations and a list of published articles.
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15
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207
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Recent Articles
1.
Cwetsch A, Gil-Sanz C
Methods Mol Biol
. 2025 Mar;
2899:171-182.
PMID: 40067624
In vivo electroporation is a technique that allows for the transfection of specific neuronal progenitor pools in the developing embryo or during early postnatal stages. By combining plasmid DNA injection...
2.
Cwetsch A, Ziogas I, Narducci R, Savardi A, Bolla M, Pinto B, et al.
Brain Commun
. 2022 May;
4(3):fcac091.
PMID: 35528232
Protocadherin 19 gene-related epilepsy or protocadherin 19 clustering epilepsy is an infantile-onset epilepsy syndrome characterized by psychiatric (including autism-related), sensory, and cognitive impairment of varying degrees. Protocadherin 19 clustering epilepsy...
3.
Gonzalez-Martinez J, Cwetsch A, Gilabert-Juan J, Gomez J, Garaulet G, Schneider P, et al.
Cell Death Differ
. 2022 Jan;
29(8):1474-1485.
PMID: 35058575
Alteration of centrosome function and dynamics results in major defects during chromosome segregation and is associated with primary autosomal microcephaly (MCPH). Despite the knowledge accumulated in the last few years,...
4.
Gonzalez-Martinez J, Cwetsch A, Martinez-Alonso D, Lopez-Sainz L, Almagro J, Melati A, et al.
JCI Insight
. 2021 Jul;
6(16).
PMID: 34237032
Congenital microcephaly (MCPH) is a neurodevelopmental disease associated with mutations in genes encoding proteins involved in centrosomal and chromosomal dynamics during mitosis. Detailed MCPH pathogenesis at the cellular level is...
5.
Moreau M, Saillour Y, Cwetsch A, Pierani A, Causeret F
Development
. 2021 Jun;
148(14).
PMID: 34170322
In the developing cerebral cortex, how progenitors that seemingly display limited diversity end up producing a vast array of neurons remains a puzzling question. The prevailing model suggests that temporal...
6.
Trovato F, Parra R, Pracucci E, Landi S, Cozzolino O, Nardi G, et al.
Nat Commun
. 2020 Dec;
11(1):6194.
PMID: 33273479
Genetic mosaicism, a condition in which an organ includes cells with different genotypes, is frequently present in monogenic diseases of the central nervous system caused by the random inactivation of...
7.
Szczurkowska J, Lee S, Guo A, Cwetsch A, Khan T, Rao S, et al.
Cell Rep
. 2020 Apr;
31(2):107519.
PMID: 32294442
Studies in cultured neurons have established that axon specification instructs neuronal polarization and is necessary for dendrite development. However, dendrite formation in vivo occurs when axon formation is prevented. The...
8.
Arai Y, Cwetsch A, Coppola E, Cipriani S, Nishihara H, Kanki H, et al.
Cell Rep
. 2019 Oct;
29(3):645-658.e5.
PMID: 31618633
Changes in transcriptional regulation through cis-regulatory elements are thought to drive brain evolution. However, how this impacts the identity of primate cortical neurons is still unresolved. Here, we show that...
9.
Costa R, Martins H, Martins L, Cwetsch A, Mele M, Pedro J, et al.
Cell Rep
. 2019 Jul;
28(4):864-876.e6.
PMID: 31340150
Ribosomes and a subset of cellular mRNAs are trafficked into axons of developing neurons. The axonal localization of translational machinery allows new proteins to be rapidly and locally synthesized during...
10.
Naskar S, Narducci R, Balzani E, Cwetsch A, Tucci V, Cancedda L
Nat Commun
. 2019 Mar;
10(1):1195.
PMID: 30867422
The development of functional synapses is a sequential process preserved across many brain areas. Here, we show that glutamatergic postsynaptic currents anticipated GABAergic currents in Layer II/III of the rat...