Andrey Karshikoff
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Explore the profile of Andrey Karshikoff including associated specialties, affiliations and a list of published articles.
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20
Citations
245
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Recent Articles
11.
Irimia A, Vellieux F, Madern D, Zaccai G, Karshikoff A, Tibbelin G, et al.
J Mol Biol
. 2003 Dec;
335(1):343-56.
PMID: 14659762
The crystal structure of malate dehydrogenase from the hyperthermophilic archaeon Archeoglobus fulgidus, in complex with its cofactor NAD, was solved at 2.9A resolution. The crystal structure shows a compact homodimer...
12.
Koumanov A, Zachariae U, Engelhardt H, Karshikoff A
Eur Biophys J
. 2003 Jul;
32(8):689-702.
PMID: 12879311
A continuum model, based on the Poisson-Nernst-Planck (PNP) theory, is applied to simulate steady-state ion flux through protein channels. The PNP equations are modified to explicitly account (1) for the...
13.
Christova P, Todorova K, Timtcheva I, Nacheva G, Karshikoff A, Nikolov P
Z Naturforsch C J Biosci
. 2003 Apr;
58(3-4):288-94.
PMID: 12710743
Unfolding/folding transitions of recombinant human interferon-gamma (hIFNgamma) in urea and guanidine chloride (Gn.HCl) solutions were studied by fluorescence spectroscopy. At pH 7.4 Gn.HCl was a much more efficient denaturant (midpoint...
14.
Nacheva G, Todorova K, Boyanova M, Berzal-Herranz A, Karshikoff A, Ivanov I
Arch Biochem Biophys
. 2003 Apr;
413(1):91-8.
PMID: 12706345
The significance of the C-terminal part of human interferon gamma (hIFNgamma) for its biological activity was studied by 3(')-end gene mutagenesis. A series of nine derivative genes obtained by systemic...
15.
Koumanov A, Benach J, Atrian S, Gonzalez-Duarte R, Karshikoff A, Ladenstein R
Proteins
. 2003 Mar;
51(2):289-98.
PMID: 12660997
The ionization properties of the active site residues in Drosophila lebanonensis alcohol dehydrogenase (DADH) were investigated theoretically by using an approach developed to account for multiple locations of the hydrogen...
16.
Milev S, Gorfe A, Karshikoff A, Clubb R, Bosshard H, Jelesarov I
Biochemistry
. 2003 Mar;
42(12):3492-502.
PMID: 12653553
Sequence-specific DNA recognition by bacterial integrase Tn916 involves structural rearrangements of both the protein and the DNA duplex. Energetic contributions from changes of conformation, thermal motions and soft vibrational modi...
17.
Milev S, Gorfe A, Karshikoff A, Clubb R, Bosshard H, Jelesarov I
Biochemistry
. 2003 Mar;
42(12):3481-91.
PMID: 12653552
The DNA binding domain of the transposon Tn916 integrase (INT-DBD) binds to its DNA target site by positioning the face of a three-stranded antiparallel beta-sheet within the major groove. Binding...
18.
Kundrotas P, Karshikoff A
Protein Sci
. 2002 Jun;
11(7):1681-6.
PMID: 12070320
Existing models of the denatured state of proteins consider only one possible spatial distribution of protein charges and therefore are applicable to a limited number of cases. In this article,...
19.
Zachariae U, Koumanov A, Engelhardt H, Karshikoff A
Protein Sci
. 2002 May;
11(6):1309-19.
PMID: 12021430
The functional properties of the anion-selective porin Omp32 from the bacterium Delftia acidovorans, formerly Comamonas acidovorans, are determined by the particularly narrow channel constriction and the electrostatic field inside and...
20.
Koumanov A, Ruterjans H, Karshikoff A
Proteins
. 2001 Dec;
46(1):85-96.
PMID: 11746705
Irregular (nonsigmoidal) ionization behavior of titratable groups in proteins is analyzed theoretically, using a computational algorithm designed to count explicitly for tautomers of titratable groups and different locations of polar...