Andrey Bortsov
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Explore the profile of Andrey Bortsov including associated specialties, affiliations and a list of published articles.
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17
Citations
267
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Recent Articles
1.
Wang Y, Kim S, Klein M, Chen J, Gu E, Smith S, et al.
Sci Transl Med
. 2024 Apr;
16(742):eadj0395.
PMID: 38598615
Chronic primary pain conditions (CPPCs) affect over 100 million Americans, predominantly women. They remain ineffectively treated, in large part because of a lack of valid animal models with translational relevance....
2.
Kenney M, Wilson S, Shah N, Bortsov A, Smith W, Little J, et al.
J Pain
. 2023 Aug;
25(1):153-164.
PMID: 37544393
Pain is the primary symptomatic manifestation of sickle cell disease (SCD), an inherited hemoglobinopathy. The characteristics that influence pain experiences and outcomes in SCD are not fully understood. The primary...
3.
Zhao J, Huh Y, Bortsov A, Diatchenko L, Ji R
Pharmacol Ther
. 2023 Jun;
248:108476.
PMID: 37307899
It is generally believed that immune activation can elicit pain through production of inflammatory mediators that can activate nociceptive sensory neurons. Emerging evidence suggests that immune activation may also contribute...
4.
Buchheit T, Huh Y, Breglio A, Bang S, Xu J, Matsuoka Y, et al.
Brain Behav Immun
. 2023 May;
111:298-311.
PMID: 37150265
Chemotherapy-induced peripheral neuropathy (CIPN) is the most prevalent neurological complication of chemotherapy for cancer, and has limited effective treatment options. Autologous conditioned serum (ACS) is an effective biologic therapy used...
5.
Suttle A, Wang P, Dias F, Zhang Q, Luo Y, Simmons L, et al.
J Pain
. 2022 Dec;
24(5):782-795.
PMID: 36509176
Temporomandibular disorder (TMD) pain that involves inflammation and injury in the temporomandibular joint (TMJ) and/or masticatory muscle is the most common form of orofacial pain. We recently found that transient...
6.
Carey E, Geller E, Rapkin A, Farb D, Cutting H, Akaninwor J, et al.
Ann Med
. 2022 Oct;
54(1):2885-2897.
PMID: 36269028
Background: Limited data are available to establish evidence-based management protocols for vestibulodynia (VBD), a chronic vulvar pain condition that affects approximately 14 million women in the U.S. For the purposes...
7.
Yeo M, Chen Y, Jiang C, Chen G, Wang K, Chandra S, et al.
Nat Commun
. 2021 Oct;
12(1):6208.
PMID: 34707084
Inhibitory GABA-ergic neurotransmission is fundamental for the adult vertebrate central nervous system and requires low chloride concentration in neurons, maintained by KCC2, a neuroprotective ion transporter that extrudes intracellular neuronal...
8.
Luo X, Chen O, Wang Z, Bang S, Ji J, Lee S, et al.
Neuron
. 2021 Sep;
109(17):2691-2706.e5.
PMID: 34473953
Although sex dimorphism is increasingly recognized as an important factor in pain, female-specific pain signaling is not well studied. Here we report that administration of IL-23 produces mechanical pain (mechanical...
9.
Chen Y, Wang Z, Yeo M, Zhang Q, Lopez-Romero A, Ding H, et al.
Gastroenterology
. 2021 Apr;
161(1):301-317.e16.
PMID: 33819485
Background & Aims: Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus....
10.
Gaynor S, Bortsov A, Bair E, Fillingim R, Greenspan J, Ohrbach R, et al.
Pain
. 2020 Dec;
162(5):1528-1538.
PMID: 33259458
Traditional classification and prognostic approaches for chronic pain conditions focus primarily on anatomically based clinical characteristics not based on underlying biopsychosocial factors contributing to perception of clinical pain and future...