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Andrew Willetts

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1.
Willetts A
Microorganisms . 2024 Feb; 12(2). PMID: 38399793
A Special Issue of devoted to 'Microbial Biocatalysis and Biodegradation' would be incomplete without some form of acknowledgement of the many important roles that dioxygen-dependent enzymes (principally mono- and dioxygenases)...
2.
Willetts A
Molecules . 2023 Nov; 28(21). PMID: 37959669
The role of cofactor recycling in determining the efficiency of artificial biocatalytic cascades has become paramount in recent years. Closed-loop cofactor recycling, which initially emerged in the 1990s, has made...
3.
Willetts A
Microorganisms . 2023 Jan; 11(1). PMID: 36677363
Using highly purified enzyme preparations throughout, initial kinetic studies demonstrated that the isoenzymic 2,5- and 3,6-diketocamphane mono-oxygenases from ATCC 17453 and the LuxAB luciferase from ATCC 7744 exhibit commonality in...
4.
Richards L, Nash A, Willetts A, Entwistle C, de Leeuw N
RSC Adv . 2022 May; 8(11):5728-5739. PMID: 35557986
A classical all-atom force field has been developed for 2,4,6-trinitroethylbenzene and 2,4-dinitroethylbenzene and applied in molecular dynamics simulations of the two pure and two mixed plasticizer systems. Bonding parameters and...
5.
Willetts A
Microorganisms . 2021 Dec; 9(12). PMID: 34946195
Researching the involvement of molecular oxygen in the degradation of the naturally occurring bicyclic terpene camphor has generated a six-decade history of fascinating monooxygenase biochemistry. While an extensive bibliography exists...
6.
Willetts A
Microorganisms . 2019 Sep; 7(10). PMID: 31561477
The relative importance of camphor (CAM) plasmid-coded putidaredoxin reductase (PdR) and the chromosome-coded flavin reductases Frp1, Frp2 and Fred for supplying reduced FMN (FNR) to the enantiocomplementary 2,5- and 3,6-diketocamphane...
7.
Willetts A
Microorganisms . 2018 Dec; 7(1). PMID: 30577535
The CAM plasmid-coded isoenzymic diketocamphane monooxygenases induced in ATCC 17453 (NCIMB 10007) by growth of the bacterium on the bicyclic monoterpene ()-camphor are notable both for their interesting history, and...
8.
Willetts A, Masters P, Steadman C
Microorganisms . 2018 May; 6(2). PMID: 29735926
For the first time, the differential rates of synthesis of all the key monooxygenases involved in the catabolism by NCIMB 10007 of bicyclic ()-camphor to ∆-3,4,4-trimethylpimelyl-CoA, the first aliphatic pathway...
9.
Willetts A, Kelly D
Microorganisms . 2017 Sep; 5(3). PMID: 28878173
I thank Drs. Littlechild and Isupov for their recent comments, which are considered below. Before addressing these specifically, their correspondence raises two more general issues which require initial clarification.[...].
10.
Willetts A, Kelly D
Microorganisms . 2016 Oct; 4(4). PMID: 27754389
The progressive titres of key monooxygenases and their requisite native donors of reducing power were used to assess the relative contribution of various camphor plasmid (CAM plasmid)- and chromosome-coded activities...