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Andrew Wiechert

Explore the profile of Andrew Wiechert including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 204
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Recent Articles
1.
Thiagarajan P, Sinyuk M, Turaga S, Mulkearns-Hubert E, Hale J, Rao V, et al.
Nat Commun . 2018 Feb; 9(1):578. PMID: 29422613
Tumors adapt their phenotypes during growth and in response to therapies through dynamic changes in cellular processes. Connexin proteins enable such dynamic changes during development, and their dysregulation leads to...
2.
Saygin C, Wiechert A, Rao V, Alluri R, Connor E, Thiagarajan P, et al.
J Exp Med . 2017 Aug; 214(9):2715-2732. PMID: 28838952
Effective targeting of cancer stem cells (CSCs) requires neutralization of self-renewal and chemoresistance, but these phenotypes are often regulated by distinct molecular mechanisms. Here we report the ability to target...
3.
Wiechert A, Saygin C, Thiagarajan P, Rao V, Hale J, Gupta N, et al.
Oncotarget . 2016 Apr; 7(21):30511-22. PMID: 27105520
The mainstay of treatment for ovarian cancer is platinum-based cytotoxic chemotherapy. However, therapeutic resistance and recurrence is a common eventuality for nearly all ovarian cancer patients, resulting in poor median...
4.
Mahdi H, Alhassani A, Lockhart D, Al-Fatlawi H, Wiechert A
Int J Gynecol Cancer . 2016 Jan; 26(2):276-81. PMID: 26807563
Objectives: To examine the effect of body mass index (BMI) on postoperative 30-day morbidity and mortality after surgery for ovarian cancer (OC). Methods: Patients with OC were identified from the...
5.
Mahdi H, Wiechert A, Lockhart D, Rose P
Int J Gynecol Cancer . 2015 Jun; 25(7):1216-23. PMID: 26076218
Objective: To examine the effect of age on postoperative 30-day morbidity and mortality after surgery for ovarian cancer. Methods: The American College of Surgeons National Surgical Quality Improvement Program files...
6.
Thiagarajan P, Hitomi M, Hale J, Alvarado A, Otvos B, Sinyuk M, et al.
Stem Cells . 2015 Apr; 33(7):2114-2125. PMID: 25827713
Advanced cancers display cellular heterogeneity driven by self-renewing, tumorigenic cancer stem cells (CSCs). The use of cell lines to model CSCs is challenging due to the difficulty of identifying and...
7.
Clark R, Growdon W, Wiechert A, Boruta D, Del Carmen M, Goodman A, et al.
Gynecol Oncol . 2013 Jun; 130(3):407-10. PMID: 23747329
Objective: Hospital readmissions are common, costly and increasingly viewed as adverse events. In gynecologic oncology, data on readmissions are limited. The goal of this study was to examine the patient,...