Andrew Walakira
Overview
Explore the profile of Andrew Walakira including associated specialties, affiliations and a list of published articles.
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12
Citations
191
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Recent Articles
1.
Skubic C, Trcek H, Nassib P, Kreft T, Walakira A, Pohar K, et al.
iScience
. 2024 Sep;
27(9):110651.
PMID: 39262789
Sterols from cholesterol synthesis are crucial for cholesterol production, but also have individual roles difficult to assess due to essentiality of cholesterol. We developed HepG2 cell models with knockouts (KOs)...
2.
Integrative computational modeling to unravel novel potential biomarkers in hepatocellular carcinoma
Walakira A, Skubic C, Nadizar N, Rozman D, Rezen T, Mraz M, et al.
Comput Biol Med
. 2023 Apr;
159:106957.
PMID: 37116239
Hepatocellular carcinoma (HCC) is a major health problem around the world. The management of this disease is complicated by the lack of noninvasive diagnostic tools and the few treatment options...
3.
Walakira A, Ocira J, Duroux D, Fouladi R, Moskon M, Rozman D, et al.
BMC Bioinformatics
. 2022 Feb;
23(1):57.
PMID: 35105309
Genes and gene products do not function in isolation but as components of complex networks of macromolecules through physical or biochemical interactions. Dependencies of gene mutations on genetic background (i.e.,...
4.
Walakira A, Rozman D, Rezen T, Mraz M, Moskon M
Comput Struct Biotechnol J
. 2021 Jul;
19:3521-3530.
PMID: 34194675
Omics data can be integrated into a reference model using various model extraction methods (MEMs) to yield context-specific genome-scale metabolic models (GEMs). How to chose the appropriate MEM, thresholding rule...
5.
Nsobya S, Walakira A, Namirembe E, Kiggundu M, Nankabirwa J, Ruhamyankaka E, et al.
Malar J
. 2021 Jan;
20(1):4.
PMID: 33386076
Background: Rapid diagnostic tests (RDTs) play a key role in malaria case management. The most widely used RDT identifies Plasmodium falciparum based on immunochromatographic recognition of P. falciparum histidine-rich protein...
6.
Kakande E, Greenhouse B, Bajunirwe F, Drakeley C, Nankabirwa J, Walakira A, et al.
Malar J
. 2020 Jan;
19(1):21.
PMID: 31941490
Background: Multiple red blood cell (RBC) variants appear to offer protection against the most severe forms of Plasmodium falciparum malaria. Associations between these variants and uncomplicated malaria are less clear....
7.
Mpimbaza A, Walakira A, Ndeezi G, Katahoire A, Karamagi C, Nsobya S, et al.
PLoS One
. 2018 Sep;
13(9):e0203229.
PMID: 30222732
Background: Evidence for association between sickle cell and alpha thalassemia trait and severe malaria is compelling. However, for these polymorphisms associations with uncomplicated malaria, and for G6PD deficiency associations with...
8.
Asua V, Tukwasibwe S, Conrad M, Walakira A, Nankabirwa J, Mugenyi L, et al.
Am J Trop Med Hyg
. 2017 Oct;
97(3):753-757.
PMID: 28990911
Contributions of species other than to human malaria in sub-Saharan Africa are uncertain. We collected blood from children aged 6 months to 10 years diagnosed with malaria by Giemsa-stained blood...
9.
Walakira A, Tukwasibwe S, Kiggundu M, Verra F, Kakeeto P, Ruhamyankaka E, et al.
Infect Genet Evol
. 2017 Sep;
55:281-287.
PMID: 28939159
A number of human genetic polymorphisms are prevalent in tropical populations and appear to offer protection against symptomatic and/or severe malaria. We compared the prevalence of four polymorphisms, the sickle...
10.
Tumwebaze P, Tukwasibwe S, Taylor A, Conrad M, Ruhamyankaka E, Asua V, et al.
J Infect Dis
. 2017 Jan;
215(4):631-635.
PMID: 28039354
We assessed Plasmodium falciparum drug resistance markers in parasites collected in 2012, 2013, and 2015 at 3 sites in Uganda. The prevalence and frequency of parasites with mutations in putative...