Andrew Stirn
Overview
Explore the profile of Andrew Stirn including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
24
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0
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Recent Articles
1.
Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox
Schertzer M, Stirn A, Isaev K, Pereira L, Das A, Harbison C, et al.
bioRxiv
. 2023 Sep;
PMID: 37745416
Alternative splicing is an essential mechanism for diversifying proteins, in which mature RNA isoforms produce proteins with potentially distinct functions. Two major challenges in characterizing the cellular function of isoforms...
2.
Wessels H, Stirn A, Mendez-Mancilla A, Kim E, Hart S, Knowles D, et al.
Nat Biotechnol
. 2023 Jul;
42(4):628-637.
PMID: 37400521
Transcriptome engineering applications in living cells with RNA-targeting CRISPR effectors depend on accurate prediction of on-target activity and off-target avoidance. Here we design and test ~200,000 RfxCas13d guide RNAs targeting...
3.