Andrew Sawyer
Overview
Explore the profile of Andrew Sawyer including associated specialties, affiliations and a list of published articles.
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10
Citations
359
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0
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Recent Articles
1.
Fant C, Levandowski C, Gupta K, Maas Z, Moir J, Rubin J, et al.
Mol Cell
. 2020 Apr;
78(4):785-793.e8.
PMID: 32229306
RNA polymerase II (RNAPII) transcription is governed by the pre-initiation complex (PIC), which contains TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, RNAPII, and Mediator. After initiation, RNAPII enzymes pause after transcribing...
2.
Kumar M, Du J, Lagoudas G, Jiao Y, Sawyer A, Drummond D, et al.
Cell Rep
. 2018 Nov;
25(6):1458-1468.e4.
PMID: 30404002
Tumor ecosystems are composed of multiple cell types that communicate by ligand-receptor interactions. Targeting ligand-receptor interactions (for instance, with immune checkpoint inhibitors) can provide significant benefits for patients. However, our...
3.
The role of myeloid cell-derived PDGF-B in neotissue formation in a tissue-engineered vascular graft
Onwuka E, Best C, Sawyer A, Yi T, Heuer E, Sams M, et al.
Regen Med
. 2017 May;
12(3):249-261.
PMID: 28524773
Aim: Inflammatory myeloid lineage cells mediate neotissue formation in tissue-engineered vascular grafts, but the molecular mechanism is not completely understood. We examined the role of vasculogenic PDGF-B in tissue-engineered vascular...
4.
Geurden T, Bartram D, Vanimisetti H, Fanke J, Camuset P, Devos J, et al.
Vet Parasitol
. 2017 Mar;
237:104-109.
PMID: 28259556
A randomized clinical study was conducted in a total of 45 commercial dairy farms in France (14 farms), Germany (28 farms) and the UK (3 farms) to evaluate the effect...
5.
Sawyer A, Cannon J, Wang H
Ann Emerg Med
. 2016 Jun;
68(1):e7-8.
PMID: 27343678
No abstract available.
6.
Wang Y, Ghali J, Zhang G, Hu M, Wang Y, Sawyer A, et al.
Nephrology (Carlton)
. 2015 Oct;
21(2):81-5.
PMID: 26461175
Regulatory T cells (Tregs) have been recognized as having a major role in maintaining peripheral tolerance and preventing and limiting autoimmune and chronic inflammatory diseases. Tregs derive from the thymus...
7.
Polhill T, Zhang G, Hu M, Sawyer A, Zhou J, Saito M, et al.
J Am Soc Nephrol
. 2012 Jun;
23(8):1303-8.
PMID: 22677553
Regulatory T cells (Tregs) help protect against autoimmune renal injury. The use of agonist antibodies and antibody/cytokine combinations to expand Tregs in vivo may have therapeutic potential for renal disease....
8.
Wang Y, Zhang G, Hu M, Polhill T, Sawyer A, Zhou J, et al.
J Am Soc Nephrol
. 2012 Apr;
23(6):1058-67.
PMID: 22491420
Autoreactive T cells play a pivotal role in the pathogenesis of autoimmune kidney disease. T cell vaccination (TCV) may limit autoimmune disease and induce CD8+ regulatory T cells (Tregs). We...
9.
Zhou J, Wang Y, Lee V, Phoon R, Zhang G, Wang Y, et al.
Int J Clin Exp Med
. 2012 Feb;
5(1):24-33.
PMID: 22328945
Monocytes utilise a variety of chemokines to traffic to atherosclerotic plaques. CX3C chemokine ligand 1 (CX3CL1 & Fractalkine) and its receptor CX3CR1 and monocyte chemoattractant protein 1 (CCL2) have been...
10.
Tian W, Sawyer A, Kocaoglu F, Kyriakides T
Am J Pathol
. 2011 Jun;
179(2):860-8.
PMID: 21704005
Thrombospondin (TSP)-2-null mice have an altered brain foreign body response (FBR) characterized by increases in inflammation, extracellular matrix deposition, and leakage of the blood-brain barrier (BBB). In the present study,...