Andrew S Mikhail
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Explore the profile of Andrew S Mikhail including associated specialties, affiliations and a list of published articles.
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41
Citations
425
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Recent Articles
1.
Delgado J, Negussie A, Varble N, Mikhail A, Arrichiello A, Borde T, et al.
PLoS One
. 2024 Dec;
19(12):e0310345.
PMID: 39700200
Intratumoral injections often lack visibility, leading to unpredictable outcomes such as incomplete tumor coverage, off-target drug delivery and systemic toxicities. This study investigated an ultrasound (US) and x-ray imageable thermosensitive...
2.
Saccenti L, Varble N, Borde T, Mikhail A, Kassin M, Levy E, et al.
Radiol Med
. 2024 Dec;
130(2):226-234.
PMID: 39656418
Purpose: The aim of this study was to assess the feasibility of quantifying morphologic changes in tumors during immunotherapy, as a reflection of response or survival. Methods And Materials: A...
3.
Delgado J, Negussie A, Varble N, Mikhail A, Arrichiello A, Borde T, et al.
bioRxiv
. 2024 Sep;
PMID: 39282453
Intratumoral injections often lack visibility, leading to unpredictable outcomes such as incomplete tumor coverage, off-target drug delivery and systemic toxicities. This study investigated an ultrasound (US) and x-ray imageable thermosensitive...
4.
Owen J, Negussie A, Burks S, Delgado J, Mikhail A, Rivera J, et al.
Sci Rep
. 2024 Sep;
14(1):20929.
PMID: 39251665
Transarterial chemoembolization (TACE) is an image-guided minimally invasive treatment for liver cancer which involves delivery of chemotherapy and embolic material into tumor-supplying arteries to block blood flow to a liver...
5.
Delgado J, Owen J, Pritchard W, Varble N, Lopez-Silva T, Mikhail A, et al.
Sci Rep
. 2024 Sep;
14(1):20455.
PMID: 39227382
Intratumoral injections have the potential for enhanced cancer treatment efficacy while reducing costs and systemic exposure. However, intratumoral drug injections can result in substantial off-target leakage and are invisible under...
6.
Delgado J, Owen J, Pritchard W, Varble N, Lopez-Silva T, Mikhail A, et al.
Res Sq
. 2024 Jul;
PMID: 38978563
Intratumoral injections have the potential for enhanced cancer treatment efficacy while reducing costs and systemic exposure. However, intratumoral drug injections can result in substantial off-target leakage and are invisible under...
7.
Delgado J, Pritchard W, Varble N, Lopez-Silva T, Arrichiello A, Mikhail A, et al.
Sci Rep
. 2024 Jun;
14(1):13352.
PMID: 38858467
Liver cancer ranks as the fifth leading cause of cancer-related death globally. Direct intratumoral injections of anti-cancer therapeutics may improve therapeutic efficacy and mitigate adverse effects compared to intravenous injections....
8.
Delgado J, Pritchard W, Varble N, Lopez-Silva T, Arrichiello A, Mikhail A, et al.
Res Sq
. 2024 Mar;
PMID: 38496436
Liver cancer ranks as the fifth leading cause of cancer-related death globally. Direct intratumoral injections of anti-cancer therapeutics may improve therapeutic efficacy and mitigate adverse effects compared to intravenous injections....
9.
Mauda-Havakuk M, Hawken N, Owen J, Mikhail A, Starost M, Karim B, et al.
J Hepatocell Carcinoma
. 2023 Nov;
10:1973-1990.
PMID: 37954494
Objectives: Local and systemic immune responses evoked by locoregional therapies such as cryoablation are incompletely understood. The aim of this study was to characterize cryoablation-related immune response and the capacity...
10.
Mikhail A, Morhard R, Mauda-Havakuk M, Kassin M, Arrichiello A, Wood B
Adv Drug Deliv Rev
. 2023 Sep;
202:115083.
PMID: 37673217
Although systemic immunotherapy has achieved durable responses and improved survival for certain patients and cancer types, low response rates and immune system-related systemic toxicities limit its overall impact. Intratumoral (intralesional)...