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Andrew R Stiff

Explore the profile of Andrew R Stiff including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 87
Followers 0
Related Specialties
Science
Biochemistry
Oncology
Top 10 Co-Authors
Susheela Tridandapani
Joseph Markowitz
William E Carson
William E Carson 3rd
Albert de la Chapelle
Ann-Kathrin Eisfeld
Tracey Papenfuss
Jiang Wang
Vedat Yildiz
Zach Vangundy
Published In
Sci Rep
BMC Med Genomics
Protein Sci
Melanoma Res
Proc Natl Acad Sci U S A
Affiliations
Soon will be listed here.
Recent Articles
1.
Effects of epigenetic therapy on natural killer cell function and development in hematologic malignancy
Lordo M, Stiff A, Oakes C, Mundy-Bosse B
J Leukoc Biol . 2023 Mar; 113(5):518-524. PMID: 36860165
Epigenetic therapy is an emerging field in the treatment of human cancer, including hematologic malignancies. This class of therapeutic agents approved by the US Food and Drug Administration for cancer...
2.
Neuroblastoma RAS viral oncogene homolog mRNA is differentially spliced to give five distinct isoforms: implications for melanoma therapy
Duggan M, Regan-Fendt K, Olaverria Salavaggione G, Howard J, Stiff A, Sabella J, et al.
Melanoma Res . 2019 May; 29(5):491-500. PMID: 31116161
Neuroblastoma RAS viral oncogene homolog is a commonly mutated oncogene in melanoma, and therapeutic targeting of neuroblastoma RAS viral oncogene homolog has proven difficult. We characterized the expression and phenotypic...
3.
Author Correction: Nitric oxide mediated inhibition of antigen presentation from DCs to CD4 T cells in cancer and measurement of STAT1 nitration
Markowitz J, Wang J, Vangundy Z, You J, Yildiz V, Yu L, et al.
Sci Rep . 2018 Mar; 8(1):4203. PMID: 29511220
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
4.
Nitric oxide mediated inhibition of antigen presentation from DCs to CD4 T cells in cancer and measurement of STAT1 nitration
Markowitz J, Wang J, Vangundy Z, You J, Yildiz V, Yu L, et al.
Sci Rep . 2017 Nov; 7(1):15424. PMID: 29133913
Myeloid derived suppressor cells (MDSC) produce nitric oxide (NO) and inhibit dendritic cell (DC) immune responses in cancer. DCs present cancer cell antigens to CD4 T cells through Jak-STAT signal...
5.
Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma
Duggan M, Stiff A, Bainazar M, Regan K, Olaverria Salavaggione G, Maharry S, et al.
Proc Natl Acad Sci U S A . 2017 Aug; 114(36):9629-9634. PMID: 28827320
Activating mutations in BRAF are found in 50% of melanomas and although treatment with BRAF inhibitors (BRAFi) is effective, resistance often develops. We now show that recently discovered NRAS isoform...
6.
Structural characterization of NRAS isoform 5
Markowitz J, Mal T, Yuan C, Courtney N, Patel M, Stiff A, et al.
Protein Sci . 2016 Mar; 25(5):1069-74. PMID: 26947772
It was recently discovered that the NRAS isoform 5 (20 amino acids) is expressed in melanoma and results in a more aggressive cell phenotype. This novel isoform is responsible for...
7.
Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12
Campbell A, Regan K, Bhave N, Pattanayak A, Parihar R, Stiff A, et al.
BMC Med Genomics . 2015 Oct; 8:66. PMID: 26470881
Background: Traditionally, the CD56(dim)CD16(+) subset of Natural Killer (NK) cells has been thought to mediate cellular cytotoxicity with modest cytokine secretion capacity. However, studies have suggested that this subset may...