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Andrew R Hart

Explore the profile of Andrew R Hart including associated specialties, affiliations and a list of published articles. Areas
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Articles 49
Citations 1898
Followers 0
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Recent Articles
1.
Broadhurst P, Hart A
J Cancer Res Clin Oncol . 2020 Mar; 146(5):1369-1375. PMID: 32157435
Purpose: Metformin has plausible direct and indirect anti-cancer properties against pancreatic adenocarcinoma cells. However, metformin may only be efficacious in patients with inoperable pancreatic ductal adenocarcinoma (PDAC) without liver metastases....
2.
Khalili H, Hakansson N, Chan S, Chen Y, Lochhead P, Ludvigsson J, et al.
Gut . 2020 Jan; 69(9):1637-1644. PMID: 31900290
Objective: To examine the relationship between Mediterranean diet and risk of later-onset Crohn's disease (CD) or ulcerative colitis (UC). Design: We conducted a prospective cohort study of 83 147 participants...
3.
Zhang J, Haines C, Watson A, Hart A, Platt M, Pardoll D, et al.
Gut . 2019 Aug; 68(11):1971-1978. PMID: 31427405
Background: Microbiome dysbiosis predisposes to colorectal cancer (CRC), but a population-based study of oral antibiotic exposure and risk patterns is lacking. Objective: To assess the association between oral antibiotic use...
4.
Hart A, Johnson G, Huggett M
Frontline Gastroenterol . 2019 Jul; 10(3):206-207. PMID: 31288254
No abstract available.
5.
Sreedharan L, Kumar B, Jewell A, Banim P, Koulouris A, Hart A
Frontline Gastroenterol . 2019 Jul; 10(3):261-268. PMID: 31288251
Pancreatic cancer is the 11th most common cancer in the UK and has the worst prognosis of any tumour with minimal improvements in survival over recent decades. As most patients...
6.
Lam S, Alexandre L, Hardwick G, Hart A
Surgery . 2019 Apr; 166(1):28-33. PMID: 30981415
Background: Postoperative complications after esophagectomy are thought to be associated with reduced fitness. This observational study explored the associations between aerobic fitness, as determined objectively by preoperative cardiopulmonary exercise testing...
7.
Koulouris A, Luben R, Banim P, Hart A
Pancreas . 2018 Nov; 48(1):121-125. PMID: 30489447
Objectives: High dietary fiber may protect against pancreatic ductal adenocarcinoma (PDAC). We investigated associations between fiber intake and the risk of PDAC using for the first time 7-day food diaries....
8.
Broadhurst P, Hart A
Dig Dis Sci . 2018 Aug; 63(11):2840-2852. PMID: 30159732
Pancreatic ductal adenocarcinoma has the worst prognosis of any cancer. New adjuvant chemotherapies are urgently required, which are well tolerated by patients with unresectable cancers. This paper reviews the existing...
9.
Banim P, Luben R, Khaw K, Hart A
Pancreatology . 2018 Jul; 18(6):655-660. PMID: 30031691
Background: Dietary oleic acid may prevent pancreatic ductal adenocarcinoma (PDA) by reducing hyperinsulinaemia which can otherwise promote DNA damage and tumour growth. Results from previous epidemiological studies investigating oleic acid...
10.
Khalili H, Chan S, Lochhead P, Ananthakrishnan A, Hart A, Chan A
Nat Rev Gastroenterol Hepatol . 2018 May; 15(9):525-535. PMID: 29789682
Crohn's disease and ulcerative colitis, collectively known as IBD, are chronic inflammatory disorders of the gastrointestinal tract. Although the aetiopathogenesis of IBD is largely unknown, it is widely thought that...