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Andrew Parker

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Articles 160
Citations 2983
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Recent Articles
1.
Giese A, Parker A, Rehman S, Brown S, Riazuddin S, Vander Kooi C, et al.
Dis Model Mech . 2025 Mar; PMID: 40083274
Humans and mice with mutations in genes encoding CIB2 and whirlin (WHRN) are deaf. We previously reported that CIB2 binds to WHRN and is essential for stereocilia staircase architecture of...
2.
Moreland Z, Jiang F, Aguilar C, Barzik M, Gong R, Behnammanesh G, et al.
Nat Commun . 2025 Jan; 16(1):947. PMID: 39843411
Assembly of actin-based stereocilia is critical for cochlear hair cells to detect sound. To tune their mechanosensivity, stereocilia form bundles composed of graded rows of ascending height, necessitating the precise...
3.
Candy N, Parker A, Wormald P, Robinson S, Baguley C, Wickremesekera A
J Clin Neurosci . 2024 Oct; 129:110864. PMID: 39423487
No abstract available.
4.
Durand R, Bellanger C, Descamps G, Dousset C, Maiga S, Derrien J, et al.
Hemasphere . 2024 Oct; 8(10):e70016. PMID: 39380841
In multiple myeloma, as in B-cell malignancies, mono- and especially bi-allelic gene inactivation is a high-risk factor for treatment resistance, and there are currently no therapies specifically targeting p53 deficiency....
5.
Giese A, Parker A, Rehman S, Brown S, Riazuddin S, Vander Kooi C, et al.
bioRxiv . 2024 Aug; PMID: 39131343
Variations in genes coding for calcium and integrin binding protein 2 (CIB2) and whirlin cause deafness both in humans and mice. We previously reported that CIB2 binds to whirlin, and...
6.
Kornfeld B, Taha A, Kyang L, Sim H, Dewhurst S, McCloy R, et al.
J Robot Surg . 2024 May; 18(1):226. PMID: 38806847
We present a cohort review of TORS resection for HPV-associated oropharyngeal squamous cell carcinoma (OPSCC) and its associated oncological outcomes spanning a 10-year period. A retrospective case series review was...
7.
Filipe E, Velayuthar S, Philp A, Nobis M, Latham S, Parker A, et al.
Adv Sci (Weinh) . 2024 Apr; 11(23):e2307963. PMID: 38602451
In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter...
8.
Soudais C, Schaus R, Bachelet C, Minet N, Mouasni S, Garcin C, et al.
Nat Commun . 2024 Mar; 15(1):1982. PMID: 38438357
De novo synthesis of the pyrimidine, cytidine triphosphate (CTP), is crucial for DNA/RNA metabolism and depends on the CTP synthetases, CTPS1 and -2. Partial CTPS1 deficiency in humans has previously...
9.
Durand R, Bellanger C, Kervoelen C, Tessoulin B, Dousset C, Menoret E, et al.
Haematologica . 2024 Feb; 109(8):2574-2584. PMID: 38385294
Innovative therapeutic strategies have emerged over the past decade to improve outcomes for most lymphoma patients. Nevertheless, the aggressive presentation seen in high-risk mantle cell lymphoma (MCL) patients remains an...
10.
Murray C, Coyle B, Morgan H, Marder I, Woods D, Haughey T, et al.
BMJ Open . 2024 Jan; 14(1):e075792. PMID: 38296285
Objective: To develop an international consensus statement to advise on designing, delivering and evaluating sport-based interventions (SBIs) aimed at promoting social, psychological and physical well-being in prison. Design: Modified Delphi...