Andrew P Stone
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Explore the profile of Andrew P Stone including associated specialties, affiliations and a list of published articles.
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10
Citations
90
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Recent Articles
1.
Becker I, Barrachina M, Lykins J, Camacho V, Stone A, Chua B, et al.
bioRxiv
. 2024 Dec;
PMID: 39677616
One Sentence Summary: TGFβ1 is released from megakaryocytes via RhoA-mediated secretory autophagy, and targeting this process can alleviate fibrosis progression in a preclinical mouse model of myelofibrosis.
2.
Stone A, Rand E, Thornes G, Kay A, Barnes A, Hitchcock I, et al.
Stem Cell Res Ther
. 2024 Jun;
15(1):178.
PMID: 38886845
Background: Bone marrow stromal cells (BMSCs) are highly heterogeneous, which may reflect their diverse biological functions, including tissue maintenance, haematopoietic support and immune control. The current understanding of the mechanisms...
3.
Tilburg J, Stone A, Billingsley J, Scoville D, Pavenko A, Liang Y, et al.
Res Pract Thromb Haemost
. 2023 May;
7(4):100158.
PMID: 37255850
Background: While megakaryocytes are known for making platelets, recent single-cell RNA sequencing data have revealed subpopulations of megakaryocytes with predicted immunoregulatory and bone marrow niche-supporting roles. Although these studies uncovered...
4.
Kay A, Fox J, Hewitson J, Stone A, Robertson S, James S, et al.
Front Immunol
. 2022 Dec;
13:1111042.
PMID: 36582232
[This corrects the article DOI: 10.3389/fimmu.2022.903796.].
5.
Khan A, Rodriguez-Romera A, Reyat J, Olijnik A, Colombo M, Wang G, et al.
Cancer Discov
. 2022 Nov;
13(2):364-385.
PMID: 36351055
Significance: We present a human bone marrow organoid that supports the growth of primary cells from patients with myeloid and lymphoid blood cancers. This model allows for mechanistic studies of...
6.
Kay A, Fox J, Hewitson J, Stone A, Robertson S, James S, et al.
Front Immunol
. 2022 Jun;
13:903796.
PMID: 35734183
Heterogeneity of bone marrow mesenchymal stromal cells (MSCs, frequently referred to as "mesenchymal stem cells") clouds biological understanding and hampers their clinical development. In MSC cultures most commonly used in...
7.
Stone A, Nikols E, Freire D, Machlus K
J Thromb Haemost
. 2022 May;
20(7):1550-1558.
PMID: 35506218
Platelet-derived extracellular vesicles (PEVs) were originally studied for their potential as regulators of coagulation, a function redundant with that of their parent cells. However, as the understanding of the diverse...
8.
Stone A, Nascimento T, Barrachina M
Blood
. 2021 Sep;
139(4):483-491.
PMID: 34587234
Megakaryocytes (MKs), the largest of the hematopoietic cells, are responsible for producing platelets by extending and depositing long proplatelet extensions into the bloodstream. The traditional view of megakaryopoiesis describes the...
9.
Herd O, Rani G, Hewitson J, Hogg K, Stone A, Cooper N, et al.
Blood Adv
. 2021 Aug;
5(23):4877-4889.
PMID: 34428275
Immune thrombocytopenia (ITP) is an acquired autoimmune condition characterized by both reduced platelet production and the destruction of functionally normal platelets by sustained attack from the immune system. However, the...
10.
Minhas G, Bawdon D, Herman R, Rudden M, Stone A, James A, et al.
Elife
. 2018 Jul;
7.
PMID: 29966586
Mammals produce volatile odours that convey different types of societal information. In , this is now recognised as body odour, a key chemical component of which is the sulphurous thioalcohol,...