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Andrew P K Wodrich

Explore the profile of Andrew P K Wodrich including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 31
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Recent Articles
1.
Wodrich A, Harris B, Giniger E
Biol Open . 2024 Sep; 13(10). PMID: 39292114
Reactive oxygen species (ROS) are associated with aging and neurodegeneration, but the significance of this association remains obscure. Here, using a Drosophila Cdk5 model of age-related neurodegeneration, we probe this...
2.
Wodrich A, Harris B, Giniger E
Biol Open . 2024 Jun; 13(7). PMID: 38912559
Changes in mitochondrial distribution are a feature of numerous age-related neurodegenerative diseases. In Drosophila, reducing the activity of Cdk5 causes a neurodegenerative phenotype and is known to affect several mitochondrial...
3.
Wodrich A, Harris B, Giniger E
bioRxiv . 2024 Apr; PMID: 38585927
Reactive oxygen species (ROS) are associated with aging and neurodegeneration, but the significance of this association remains obscure. Here, using a model of age-related neurodegeneration, we probe this relationship in...
4.
Wodrich A, Harris B, Giniger E
bioRxiv . 2024 Feb; PMID: 38405730
Changes in mitochondrial distribution are a feature of numerous age-related neurodegenerative diseases. In , reducing the activity of Cdk5 causes a neurodegenerative phenotype and is known to affect several mitochondrial...
5.
Wodrich A, Scott A, Giniger E
Mech Ageing Dev . 2023 Jun; 213:111839. PMID: 37354919
What is the nature of aging, and how best can we study it? Here, using a series of questions that highlight differing perspectives about the nature of aging, we ask...
6.
Wodrich A, Scott A, Shukla A, Harris B, Giniger E
Front Mol Neurosci . 2022 Mar; 15:831116. PMID: 35283733
Aging and age-related neurodegeneration are both associated with the accumulation of unfolded and abnormally folded proteins, highlighting the importance of protein homeostasis (termed proteostasis) in maintaining organismal health. To this...
7.
Hrizo S, Eicher S, Myers T, McGrath I, Wodrich A, Venkatesh H, et al.
Neurobiol Dis . 2021 Feb; 152:105299. PMID: 33600953
Triosephosphate isomerase (TPI) deficiency (Df) is a rare recessive metabolic disorder that manifests as hemolytic anemia, locomotor impairment, and progressive neurodegeneration. Research suggests that TPI Df mutations, including the "common"...