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Andrew P Hodges

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Articles 11
Citations 210
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Recent Articles
1.
Fuller C, Padayatti P, Abderrahim H, Adamiak L, Alagar N, Ananthapadmanabhan N, et al.
Proc Natl Acad Sci U S A . 2022 Jan; 119(5). PMID: 35074874
For nearly 50 years, the vision of using single molecules in circuits has been seen as providing the ultimate miniaturization of electronic chips. An advanced example of such a molecular...
2.
Liu T, Zhu B, Liu Y, Zhang X, Yin J, Li X, et al.
J Exp Med . 2020 Sep; 217(12). PMID: 32941599
Variations in many genes linked to sporadic Alzheimer's disease (AD) show abundant expression in microglia, but relationships among these genes remain largely elusive. Here, we establish isogenic human ESC-derived microglia-like...
3.
Kong Y, Gimple R, McVicar R, Hodges A, Yin J, Liu Y, et al.
Stem Cell Reports . 2020 Aug; 15(3):761-775. PMID: 32795421
One approach to understanding how tissue-specific cancers emerge is to determine the requirements for "reprograming" such neoplastic cells back to their developmentally normal primordial pre-malignant epiblast-like pluripotent state and then...
4.
Wang J, Merino D, Light N, Murphy B, Wang Y, Guo X, et al.
Cancer Res . 2019 Mar; 79(9):2208-2219. PMID: 30885981
Choroid plexus carcinoma (CPC) is a rare brain tumor that occurs most commonly in very young children and has a dismal prognosis despite intensive therapy. Improved outcomes for patients with...
5.
Moldt B, Le K, Carnathan D, Whitney J, Schultz N, Lewis M, et al.
AIDS . 2016 Jun; 30(10):1543-51. PMID: 27243773
Objective: Passive administration of broadly neutralizing antibodies has been shown to protect against both vaginal and rectal challenge in the simian/human immunodeficiency virus (SHIV)/macaque model of HIV transmission. However, the...
6.
Nemzek J, Hodges A, He Y
BMC Res Notes . 2015 Oct; 8:516. PMID: 26423575
Background: Inflammatory disease processes involve complex and interrelated systems of mediators. Determining the causal relationships among these mediators becomes more complicated when two, concurrent inflammatory conditions occur. In those cases,...
7.
Tran T, Ong E, Hodges A, Paternostro G, Piermarocchi C
BMC Syst Biol . 2014 Jun; 8:74. PMID: 24961498
Background: Many kinase inhibitors have been approved as cancer therapies. Recently, libraries of kinase inhibitors have been extensively profiled, thus providing a map of the strength of action of each...
8.
Vigil P, Stapleton A, Johnson J, Hooton T, Hodges A, He Y, et al.
mBio . 2011 May; 2(3):e00066-11. PMID: 21540363
Unlabelled: Uropathogenic Escherichia coli (UPEC) strains, which cause the majority of uncomplicated urinary tract infections (UTIs), carry a unique assortment of virulence or fitness genes. However, no single defining set...
9.
Hodges A, Woolf P, He Y
Commun Integr Biol . 2011 Feb; 3(6):549-54. PMID: 21331236
A Bayesian network expansion algorithm called BN+1 was developed to identify undocumented gene interactions in a known pathway using microarray gene expression data. In our recent paper, the BN+1 algorithm...
10.
Hodges A, Dai D, Xiang Z, Woolf P, Xi C, He Y
PLoS One . 2010 Mar; 5(3):e9513. PMID: 20209085
Signaling and regulatory pathways that guide gene expression have only been partially defined for most organisms. However, given the increasing number of microarray measurements, it may be possible to reconstruct...