Andrew Melbourne
Overview
Explore the profile of Andrew Melbourne including associated specialties, affiliations and a list of published articles.
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67
Citations
903
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Recent Articles
1.
Flouri D, Darby J, Holman S, Williams G, Vavourakis V, David A, et al.
J Physiol
. 2025 Feb;
603(5):1029-1044.
PMID: 39937834
An adequate supply of oxygen is crucial for optimal fetal growth and development. Estimation of quantitative indices that reflect tissue diffusivity and oxygenation have been enabled by advances in magnetic...
2.
Gelat P, van t Wout E, Haqhenas R, Melbourne A, David A, Mufti N, et al.
Res Sq
. 2024 Dec;
PMID: 39649159
Acoustic noise can have profound effects on wellbeing, impacting the health of the pregnant mother and the development of the fetus. Mounting evidence suggests neural memory traces are formed by...
3.
Darby J, Flouri D, Cho S, Williams G, Holman S, Meakin A, et al.
Exp Physiol
. 2024 Apr;
109(6):980-991.
PMID: 38606906
Increasing placental perfusion (PP) could improve outcomes of growth-restricted fetuses. One way of increasing PP may be by using phosphodiesterase (PDE)-5 inhibitors, which induce vasodilatation of vascular beds. We used...
4.
Melbourne A, Schabel M, David A, Roberts V
Biol Reprod
. 2024 Mar;
110(6):1065-1076.
PMID: 38442734
Although the central role of adequate blood flow and oxygen delivery is known, the lack of optimized imaging modalities to study placental structure has impeded our understanding of its vascular...
5.
Fidon L, Aertsen M, Kofler F, Bink A, David A, Deprest T, et al.
IEEE Trans Pattern Anal Mach Intell
. 2024 Jan;
46(5):3784-3795.
PMID: 38198270
Deep learning models for medical image segmentation can fail unexpectedly and spectacularly for pathological cases and images acquired at different centers than training images, with labeling errors that violate expert...
6.
Irzan H, Hutel M, OReilly H, Ourselin S, Marlow N, Melbourne A
Med Image Anal
. 2023 Dec;
92:103037.
PMID: 38056163
The preterm phenotype results from the interplay of multiple disorders affecting the brain and cognitive outcomes. Accurately characterising these interactions can reveal prematurity markers. Bayesian Networks (BNs) are powerful tools...
7.
Mufti N, Aertsen M, Thomson D, De Vloo P, Demaerel P, Deprest J, et al.
Acta Obstet Gynecol Scand
. 2023 Nov;
103(2):322-333.
PMID: 37984808
Introduction: Fetal surgery for open spina bifida (OSB) requires comprehensive preoperative assessment using imaging for appropriate patient selection and to evaluate postoperative efficacy and complications. We explored patient access and...
8.
Laureano B, Irzan H, OReilly H, Ourselin S, Marlow N, Melbourne A
Magn Reson Imaging
. 2023 Nov;
105:114-124.
PMID: 37984490
Prematurity and preterm stressors severely affect the development of infants born before 37 weeks of gestation, with increasing effects seen at earlier gestations. Although preterm mortality rates have declined due...
9.
Fidon L, Viola E, Mufti N, David A, Melbourne A, Demaerel P, et al.
Open Res Eur
. 2023 Aug;
1:123.
PMID: 37645096
Spina bifida aperta (SBA) is a birth defect associated with severe anatomical changes in the developing fetal brain. Brain magnetic resonance imaging (MRI) atlases are popular tools for studying neuropathology...
10.
Chappell J, Aughwane R, Clark A, Ourselin S, David A, Melbourne A
Placenta
. 2023 Aug;
142:56-63.
PMID: 37639951
The placenta provides the vital nutrients and removal of waste products required for fetal growth and development. Understanding and quantifying the differences in structure and function between a normally functioning...