Andrew L Paek
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Explore the profile of Andrew L Paek including associated specialties, affiliations and a list of published articles.
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19
Citations
304
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Recent Articles
11.
Islam S, Paek A, Hammer M, Rangarajan S, Ruijtenbeek R, Cooke L, et al.
Oncotarget
. 2018 Dec;
9(89):35875-35890.
PMID: 30542505
Key Points: ● MYC mediated upregulation of TPX2, KPNA2 and RanGAP1 dysregulate the spindle assembly checkpoint in drug-induced polyploid cells.● Drug-induced polyploid cells re-enter the cell cycle via multipolar mitosis,...
12.
Ballweg R, Paek A, Zhang T
Sci Rep
. 2017 Aug;
7(1):8002.
PMID: 28808338
When chemotherapy drugs are applied to tumor cells with the same or similar genotypes, some cells are killed, while others survive. This fractional killing contributes to drug resistance in cancer....
13.
Paek A, Liu J, Loewer A, Forrester W, Lahav G
Cell
. 2016 Apr;
165(3):631-42.
PMID: 27062928
Many chemotherapeutic drugs kill only a fraction of cancer cells, limiting their efficacy. We used live-cell imaging to investigate the role of p53 dynamics in fractional killing of colon cancer...
14.
URen J, Wisecaver J, Paek A, Dunn B, Hurwitz B
Genome Announc
. 2015 Jul;
3(4).
PMID: 26205854
Saccharomyces cerevisiae strain GSY2239 is derived from an industrial yeast strain used to ferment ale-style beer. We present here the 11.5-Mb draft genome sequence for this organism.
15.
Carr A, Paek A, Weinert T
Semin Cell Dev Biol
. 2011 Oct;
22(8):866-74.
PMID: 22020070
DNA replication normally follows the rules passed down from Watson and Crick: the chromosome duplicates as dictated by its antiparallel strands, base-pairing and leading and lagging strand differences. Real-life replication...
16.
Paek A, Weinert T
Mol Cell
. 2010 Nov;
40(4):505-6.
PMID: 21095580
Checkpoint proteins respond to DNA damage by halting the cell cycle until the damage is repaired. In this issue of Molecular Cell, Furuya et al. (2010) provide evidence that checkpoint...
17.
Paek A, Jones H, Kaochar S, Weinert T
Genetics
. 2010 Sep;
186(4):1161-73.
PMID: 20837992
Gross chromosomal rearrangements (GCRs) are large scale changes to chromosome structure and can lead to human disease. We previously showed in Saccharomyces cerevisiae that nearby inverted repeat sequences (∼20-200 bp...
18.
Kaochar S, Paek A, Weinert T
Science
. 2010 Aug;
329(5994):911-3.
PMID: 20724625
No abstract available.
19.
Paek A, Kaochar S, Jones H, Elezaby A, Shanks L, Weinert T
Genes Dev
. 2009 Dec;
23(24):2861-75.
PMID: 20008936
Large-scale changes (gross chromosomal rearrangements [GCRs]) are common in genomes, and are often associated with pathological disorders. We report here that a specific pair of nearby inverted repeats in budding...