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Andrew L Lux

Explore the profile of Andrew L Lux including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 20
Citations 826
Followers 0
Related Specialties
Neurology
Pediatrics
General Medicine
Top 10 Co-Authors
John P Osborne
Richard W Newton
Christopher M Verity
Eleanor Hancock
Stuart W Edwards
Anthony L Johnson
Colin R Kennedy
Finbar J K OCallaghan
Marcus Likeman
Dietz Rating
Published In
Epilepsia
Arch Dis Child
Childs Nerv Syst
Eur J Paediatr Neurol
Lancet Neurol
Affiliations
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Recent Articles
11.
Epilepsies in infancy
Alam S, Lux A
Arch Dis Child . 2012 Sep; 97(11):985-92. PMID: 22962318
To evaluate and manage epileptic seizures and other paroxysmal events in infants, it is necessary to ask five key questions: (1) Is this a type of epilepsy?; (2) What seizure...
12.
The effect of lead time to treatment and of age of onset on developmental outcome at 4 years in infantile spasms: evidence from the United Kingdom Infantile Spasms Study
OCallaghan F, Lux A, Darke K, Edwards S, Hancock E, Johnson A, et al.
Epilepsia . 2011 Jun; 52(7):1359-64. PMID: 21668442
Purpose: Infantile spasms is a severe infantile seizure disorder. Several factors affect developmental outcome, especially the underlying etiology of the spasms. Treatment also affects outcome. Both age at onset of...
13.
The underlying etiology of infantile spasms (West syndrome): information from the United Kingdom Infantile Spasms Study (UKISS) on contemporary causes and their classification
Osborne J, Lux A, Edwards S, Hancock E, Johnson A, Kennedy C, et al.
Epilepsia . 2010 Aug; 51(10):2168-74. PMID: 20726878
Purpose: To examine the underlying etiology of infantile spasms from the United Kingdom Infantile Spasms Study (UKISS), using the pediatric adaptation of ICD 10. Methods: Infants were enrolled in a...
14.
Developmental and epilepsy outcomes at age 4 years in the UKISS trial comparing hormonal treatments to vigabatrin for infantile spasms: a multi-centre randomised trial
Darke K, Edwards S, Hancock E, Johnson A, Kennedy C, Lux A, et al.
Arch Dis Child . 2010 May; 95(5):382-6. PMID: 20457702
Background: Infantile spasms is the name given to a difficult to treat, severe infantile epilepsy with high morbidity. The United Kingdom Infantile Spasms Study (UKISS) showed that absence of spasms...
15.
Antipyretic drugs do not reduce recurrences of febrile seizures in children with previous febrile seizure
Lux A
Evid Based Med . 2010 Feb; 15(1):15-6. PMID: 20176873
No abstract available.
16.
Treatment of febrile seizures: historical perspective, current opinions, and potential future directions
Lux A
Brain Dev . 2009 Oct; 32(1):42-50. PMID: 19854599
Although most febrile seizures do no harm and two-thirds of initial cases have no witnessed recurrence, the seizures cause much family anxiety, and are sometimes prolonged. In rare cases they...
17.
The influence of etiology upon ictal semiology, treatment decisions and long-term outcomes in infantile spasms and West syndrome
Lux A, Osborne J
Epilepsy Res . 2006 Jul; 70 Suppl 1:S77-86. PMID: 16828260
Studying infantile spasms is challenging because there are so many aspects of variation that introduce potential bias. These might relate to the many underlying etiologies, and variations in clinical semiology...
18.
The United Kingdom Infantile Spasms Study (UKISS) comparing hormone treatment with vigabatrin on developmental and epilepsy outcomes to age 14 months: a multicentre randomised trial
Lux A, Edwards S, Hancock E, Johnson A, Kennedy C, Newton R, et al.
Lancet Neurol . 2005 Oct; 4(11):712-7. PMID: 16239177
Background: Infantile spasms is a severe infantile seizure disorder that is difficult to treat and has a high morbidity. Absence of spasms on days 13 and 14 after randomisation is...
19.
The United Kingdom Infantile Spasms Study comparing vigabatrin with prednisolone or tetracosactide at 14 days: a multicentre, randomised controlled trial
Lux A, Edwards S, Hancock E, Johnson A, Kennedy C, Newton R, et al.
Lancet . 2004 Nov; 364(9447):1773-8. PMID: 15541450
Background: Infantile spasms, which comprise a severe infantile seizure disorder, have a high morbidity and are difficult to treat. Hormonal treatments (adrenocorticotropic hormone and prednisolone) have been the main therapy...
20.
A proposal for case definitions and outcome measures in studies of infantile spasms and West syndrome: consensus statement of the West Delphi group
Lux A, Osborne J
Epilepsia . 2004 Oct; 45(11):1416-28. PMID: 15509243
Purpose: To reach a broad consensus on case definitions, outcomes, and outcome measures that will ease future study design and facilitate comparison of data from different studies of infantile spasms...