Finbar J K OCallaghan
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Explore the profile of Finbar J K OCallaghan including associated specialties, affiliations and a list of published articles.
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20
Citations
684
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Recent Articles
1.
The metformin in tuberous sclerosis (MiTS) study: A randomised double-blind placebo-controlled trial
Amin S, Mallick A, Edwards H, Cortina-Borja M, Laugharne M, Likeman M, et al.
EClinicalMedicine
. 2021 Mar;
32:100715.
PMID: 33681737
Background: Tuberous Sclerosis Complex (TSC) is a genetic disorder characterised by the development of benign tumours secondary to loss of inhibitory regulation of the mTOR (mechanistic Target of Rapamycin) intracellular...
2.
Osborne J, Edwards S, Alber F, Hancock E, Johnson A, Kennedy C, et al.
Epilepsia
. 2019 Aug;
60(9):1861-1869.
PMID: 31418851
Objective: To determine the underlying etiologies in a contemporary cohort of infants with infantile spasms and to examine response to treatment. Methods: Identification of the underlying etiology and response to...
3.
OCallaghan F, Edwards S, Alber F, Cortina Borja M, Hancock E, Johnson A, et al.
Lancet Child Adolesc Health
. 2018 Sep;
2(10):715-725.
PMID: 30236380
Background: Infantile spasms constitute a severe form of epileptic encephalopathy. In the International Collaborative Infantile Spasms Study (ICISS), we showed that combining vigabatrin with hormonal therapy was more effective than...
4.
Wilmshurst J, Ibekwe R, OCallaghan F
Seizure
. 2016 Dec;
44:81-86.
PMID: 27989601
Purpose: This text provides an overview of how the condition "infantile spasms" has evolved in the last 175 years. Method: Key references are summarised to assimilate this review. Results: Infantile...
5.
Edwards H, Mallick A, OCallaghan F
Arch Dis Child
. 2016 Nov;
102(5):410-415.
PMID: 27864289
Background: There is little evidence about either prevention or treatment of childhood arterial ischaemic stroke (AIS). However, drugs that regulate the immune and inflammatory response could theoretically prevent occurrence or...
6.
OCallaghan F, Edwards S, Alber F, Hancock E, Johnson A, Kennedy C, et al.
Lancet Neurol
. 2016 Nov;
16(1):33-42.
PMID: 27838190
Background: Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly used treatments. We...
7.
8.
Fong C, Osborne J, Edwards S, Hemingway C, Hancock E, Johnson A, et al.
Dev Med Child Neurol
. 2013 Jun;
55(9):862-7.
PMID: 23789722
Aim: We aimed to investigate the relationship between movement disorders, changes on brain magnetic resonance imaging (MRI), and vigabatrin therapy in children with infantile spasms. Method: Retrospective review and brain...
9.
Amin S, Carter M, Edwards R, Pople I, Aquilina K, Merrifield J, et al.
Eur J Paediatr Neurol
. 2012 Nov;
17(1):36-44.
PMID: 23183057
Objectives: The indications for surgery and outcomes of patients who underwent surgical removal of subependymal giant cell astrocytomas (SEGAs) in our institution between 2000 and 2011 were reviewed. Methods: We...
10.