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Andrew Knox

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Articles 26
Citations 239
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Recent Articles
1.
Murugesan G, Paterson R, Kulkarni R, Ilkow V, Suckling R, Connolly M, et al.
Nat Commun . 2024 Nov; 15(1):10126. PMID: 39578466
The non-polymorphic HLA-E molecule offers opportunities for new universal immunotherapeutic approaches to chronic infectious diseases. Chronic Hepatitis B virus (HBV) infection is driven in part by T cell dysfunction due...
2.
Kessler-Jones A, Cieminski T, Field A, Knox A
Epilepsy Behav Rep . 2024 Sep; 28:100706. PMID: 39262922
Prosopagnosia, a neurological condition affecting perception and differentiation of faces, is categorized as either acquired or developmental (present since birth). Acquired cases of prosopagnosia are usually caused by right hemisphere...
3.
Paterson R, La Manna M, Arena De Souza V, Walker A, Gibbs-Howe D, Kulkarni R, et al.
Proc Natl Acad Sci U S A . 2024 May; 121(19):e2318003121. PMID: 38691588
Peptides presented by HLA-E, a molecule with very limited polymorphism, represent attractive targets for T cell receptor (TCR)-based immunotherapies to circumvent the limitations imposed by the high polymorphism of classical...
4.
Joshi C, Karakas C, Eschbach K, Samanta D, Auguste K, Desai V, et al.
Epilepsia Open . 2024 Feb; 9(2):785-792. PMID: 38421143
Neuromodulation via Responsive Neurostimulation (RNS) or Deep Brain Stimulation (DBS) is an emerging treatment strategy for pediatric drug-resistant epilepsy (DRE). Knowledge gaps exist in patient selection, surgical technique, and perioperative...
5.
Sherman N, Hill B, Nisbet B, Knox A, Mahoney A
JSES Int . 2024 Feb; 8(1):95-98. PMID: 38312292
No abstract available.
6.
Wallace Z, Heunis T, Paterson R, Suckling R, Grant T, Dembek M, et al.
Mol Ther . 2024 Jan; 32(3):678-688. PMID: 38219014
Naturally occurring T cells that recognize microbial peptides via HLA-E, a nonpolymorphic HLA class Ib molecule, could provide the foundation for new universal immunotherapeutics. However, confidence in the biological relevance...
7.
Trapp N, Co D, Rebsamen S, Ikonomidou C, Ahmed R, Knox A
Pediatr Neurol . 2023 Dec; 151:1-4. PMID: 38041904
Background: Bilateral Rasmussen encephalitis is a rare variant of a debilitating, typically unihemispheric disease with limited treatment options. Few cases with bilateral histopathology have been reported, all with poor seizure...
8.
Knox A, Bass N, Khakoo Y
Pediatr Neurol . 2023 Apr; 147:163-164. PMID: 37024352
No abstract available.
9.
Queiroz D, Ribeiro T, Goncalves J, Mattos L, Gerhardt E, Freitas J, et al.
Biochim Biophys Acta Mol Basis Dis . 2022 Jul; 1868(10):166475. PMID: 35777688
The overproduction of reactive oxygen species (ROS) induces oxidative stress, a well-known process associated with aging and several human pathologies, such as cancer and neurodegenerative diseases. A large number of...
10.
Verwoerd C, Limjoco J, Rajamanickam V, Knox A
J Child Neurol . 2022 Mar; 37(5):401-409. PMID: 35311411
High neonatal seizure burden is associated with worsened neurodevelopmental outcomes. We compared the efficacy of initial treatment with levetiracetam vs phenobarbital for maintaining low seizure burden in a retrospective cohort...