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Andrew Kasarskis

Explore the profile of Andrew Kasarskis including associated specialties, affiliations and a list of published articles. Areas
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Articles 92
Citations 5142
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Recent Articles
1.
Argmann C, Hou R, Ungaro R, Irizar H, Al-Taie Z, Huang R, et al.
Gut . 2022 Sep; 72(7):1271-1287. PMID: 36109152
Objective: IBD therapies and treatments are evolving to deeper levels of remission. Molecular measures of disease may augment current endpoints including the potential for less invasive assessments. Design: Transcriptome analysis...
2.
Howell D, Rogers L, Kasarskis A, Twyman K
Ann Allergy Asthma Immunol . 2022 Apr; 128(6):677-681.e7. PMID: 35367347
Background: Asthma is one of the most common chronic health conditions, and to leverage the wealth of data in the electronic medical record (EMR), it is important to be able...
3.
DiNarzo A, Houten S, Kosoy R, Huang R, Vaz F, Hou R, et al.
Gastroenterology . 2021 Nov; 162(3):828-843.e11. PMID: 34780722
Background & Aims: Polygenic and environmental factors are underlying causes of inflammatory bowel disease (IBD). We hypothesized that integration of the genetic loci controlling a metabolite's abundance, with known IBD...
4.
Argmann C, Tokuyama M, Ungaro R, Huang R, Hou R, Gurunathan S, et al.
Gastroenterology . 2021 Sep; 161(6):1953-1968.e15. PMID: 34480882
Background And Aims: Disease extent varies in ulcerative colitis (UC) from proctitis to left-sided colitis to pancolitis and is a major prognostic factor. When the extent of UC is limited...
5.
Mo A, Nagpal S, Gettler K, Haritunians T, Giri M, Haberman Y, et al.
Am J Hum Genet . 2021 Aug; 108(9):1765-1779. PMID: 34450030
An important goal of clinical genomics is to be able to estimate the risk of adverse disease outcomes. Between 5% and 10% of individuals with ulcerative colitis (UC) require colectomy...
6.
Beckmann N, Comella P, Cheng E, Lepow L, Beckmann A, Tyler S, et al.
Nat Commun . 2021 Aug; 12(1):4854. PMID: 34381049
Multisystem inflammatory syndrome in children (MIS-C) presents with fever, inflammation and pathology of multiple organs in individuals under 21 years of age in the weeks following severe acute respiratory syndrome...
7.
Scarpa J, Jiang P, Gao V, Vitaterna M, Turek F, Kasarskis A
Sci Rep . 2021 Apr; 11(1):7797. PMID: 33833255
Reduced NREM sleep in humans is associated with AD neuropathology. Recent work has demonstrated a reduction in NREM sleep in preclinical AD, pointing to its potential utility as an early...
8.
Kosoy R, Kim-Schulze S, Rahman A, Friedman J, Huang R, Peters L, et al.
Cell Mol Gastroenterol Hepatol . 2021 Apr; 12(2):599-632. PMID: 33813036
Background: Inflammatory bowel disease (IBD) is a complex disease with variable presentation, progression, and response to therapies. Current disease classification is based on subjective clinical phenotypes. The peripheral blood immunophenome...
9.
Di Narzo A, Hart A, Kosoy R, Peters L, Stojmirovic A, Cheng H, et al.
Hum Mol Genet . 2021 Feb; 30(6):514-523. PMID: 33601420
Epidemiological studies have long recognized risky behaviors as potentially modifiable factors for the onset and flares of inflammatory bowel disease (IBD); yet, the underlying mechanisms are largely unknown. Recently, the...
10.
Comella P, Gonzalez-Kozlova E, Kosoy R, Charney A, Peradejordi I, Chandrasekar S, et al.
medRxiv . 2021 Feb; PMID: 33564792
No abstract available.