Andrew J W Orry
Overview
Explore the profile of Andrew J W Orry including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
200
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0
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Recent Articles
1.
Orry A, Abagyan R
Methods Mol Biol
. 2012 Feb;
857:351-73.
PMID: 22323230
The formation of ligand-protein complexes are critical for the correct functioning of a cell. The prediction of these interactions is important for our understanding of how the cell works and...
2.
Cavasotto C, Orry A, Murgolo N, Czarniecki M, Kocsi S, Hawes B, et al.
J Med Chem
. 2008 Jan;
51(3):581-8.
PMID: 18198821
Melanin-concentrating hormone receptor 1 (MCH-R1) is a G-protein-coupled receptor (GPCR) and a target for the development of therapeutics for obesity. The structure-based development of MCH-R1 and other GPCR antagonists is...
3.
Cavasotto C, Orry A
Curr Top Med Chem
. 2007 May;
7(10):1006-14.
PMID: 17508934
Ligand-docking-based methods are starting to play a critical role in lead discovery and optimization, thus resulting in new 'drug-candidates'. They offer the possibility to go beyond the pool of existing...
4.
Orry A, Abagyan R, Cavasotto C
Drug Discov Today
. 2006 Apr;
11(5-6):261-6.
PMID: 16580603
The success or failure of a small-molecule drug discovery project ultimately lies in the choice of the scaffolds to be screened -- chosen from among the many millions of available...
5.
Cavasotto C, Orry A, Abagyan R
Proteins
. 2003 Apr;
51(3):423-33.
PMID: 12696053
G-protein coupled receptors (GPCRs) are the largest family of cell-surface receptors involved in signal transmission. Drugs associated with GPCRs represent more than one fourth of the 100 top-selling drugs and...