Andrew J Severin
Overview
Explore the profile of Andrew J Severin including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
1473
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0
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Recent Articles
11.
Bagheri H, Severin A, Rajan H
Bioinformatics
. 2020 Jun;
36(18):4699-4705.
PMID: 32579213
Motivation: As the cost of sequencing decreases, the amount of data being deposited into public repositories is increasing rapidly. Public databases rely on the user to provide metadata for each...
12.
Murugan K, Seetharam A, Severin A, Sashital D
J Biol Chem
. 2020 Mar;
295(17):5538-5553.
PMID: 32161115
Cas12a (Cpf1) is an RNA-guided endonuclease in the bacterial type V-A CRISPR-Cas anti-phage immune system that can be repurposed for genome editing. Cas12a can bind and cut dsDNA targets with...
13.
Redweik G, Daniels K, Severin A, Lyte M, Mellata M
Front Microbiol
. 2020 Feb;
10:3064.
PMID: 32010110
Cross-talk between the gut microbiota and neurochemicals affects health and well-being of animals. However, little is known about this interaction in chickens despite their importance in food production. Probiotics and...
14.
Masonbrink R, Maier T, Seetharam A, Juvale P, Baber L, Baum T, et al.
Database (Oxford)
. 2019 Nov;
2019(1).
PMID: 31680133
Soybean is an important worldwide crop, and farmers continue to experience significant yield loss due to the soybean cyst nematode (SCN), Heterodera glycines. This soil-borne roundworm parasite is rated the...
15.
Bagheri H, Muppirala U, Masonbrink R, Severin A, Rajan H
BMC Bioinformatics
. 2019 Aug;
20(1):436.
PMID: 31438850
Background: Creating a scalable computational infrastructure to analyze the wealth of information contained in data repositories is difficult due to significant barriers in organizing, extracting and analyzing relevant data. Shared...
16.
Masonbrink R, Maier T, Muppirala U, Seetharam A, Lord E, Juvale P, et al.
BMC Genomics
. 2019 Feb;
20(1):119.
PMID: 30732586
Background: Heterodera glycines, commonly referred to as the soybean cyst nematode (SCN), is an obligatory and sedentary plant parasite that causes over a billion-dollar yield loss to soybean production annually....
17.
Barnes S, Masonbrink R, Maier T, Seetharam A, Sindhu A, Severin A, et al.
Sci Rep
. 2019 Feb;
9(1):1356.
PMID: 30718603
Spliced leader trans-splicing (SLTS) plays a part in the maturation of pre-mRNAs in select species across multiple phyla but is particularly prevalent in Nematoda. The role of spliced leaders (SL)...
18.
Masonbrink R, Purcell C, Boles S, Whitehead A, Hyde J, Seetharam A, et al.
Genome Biol Evol
. 2019 Jan;
11(2):431-438.
PMID: 30657886
Abalone are one of the few marine taxa where aquaculture production dominates the global market as a result of increasing demand and declining natural stocks from overexploitation and disease. To...
19.
Purcell C, Seetharam A, Snodgrass O, Ortega-Garcia S, Hyde J, Severin A
BMC Genomics
. 2018 Jan;
19(1):31.
PMID: 29310588
Background: The assembly and annotation of a genome is a valuable resource for a species, with applications ranging from conservation genomics to gene discovery. Genomic resource development is especially important...
20.
Johnson T, Looft T, Severin A, Bayles D, Nasko D, Wommack K, et al.
mBio
. 2017 Aug;
8(4).
PMID: 28790203
Carbadox is a quinoxaline-di--oxide antibiotic fed to over 40% of young pigs in the United States that has been shown to induce phage DNA transduction ; however, the effects of...