Andrew J Pellatt
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Explore the profile of Andrew J Pellatt including associated specialties, affiliations and a list of published articles.
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29
Citations
327
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Recent Articles
1.
Gauderman W, Fu Y, Queme B, Kawaguchi E, Wang Y, Morrison J, et al.
bioRxiv
. 2025 Jan;
PMID: 39763728
A polygenic risk score (PRS) is used to quantify the combined disease risk of many genetic variants. For complex human traits there is interest in determining whether the PRS modifies,...
2.
McGee H, Bonner J, Egelston C, Fu Y, Flores O, Lindsey S, et al.
medRxiv
. 2024 Oct;
PMID: 39464256
The incidence of colorectal cancer (CRC) among individuals under age 50, or early-onset CRC (EOCRC), has been rising over the past few decades for unclear reasons, and the etiology of...
3.
Thomas C, Lin Y, Kim M, Kawaguchi E, Qu C, Um C, et al.
Epidemiology
. 2024 Sep;
36(1):126-138.
PMID: 39316822
Background: Colorectal cancer (CRC) is a common, fatal cancer. Identifying subgroups who may benefit more from intervention is of critical public health importance. Previous studies have assessed multiplicative interaction between...
4.
Wesselink E, Gauderman W, Berndt S, Brenner H, Buchanan D, Campbell P, et al.
BJC Rep
. 2024 Sep;
2(1):63.
PMID: 39233917
Background: Research on calcium intake as well as variants in the calcium sensor receptor ( gene and their interaction in relation to CRC survival is still limited. Methods: Data from...
5.
Drew D, Kim A, Lin Y, Qu C, Morrison J, Lewinger J, et al.
Sci Adv
. 2024 May;
10(22):eadk3121.
PMID: 38809988
Regular, long-term aspirin use may act synergistically with genetic variants, particularly those in mechanistically relevant pathways, to confer a protective effect on colorectal cancer (CRC) risk. We leveraged pooled data...
6.
Papadimitriou N, Kim A, Kawaguchi E, Morrison J, Diez-Obrero V, Albanes D, et al.
EBioMedicine
. 2024 May;
104:105146.
PMID: 38749303
Background: Consumption of fibre, fruits and vegetables have been linked with lower colorectal cancer (CRC) risk. A genome-wide gene-environment (G × E) analysis was performed to test whether genetic variants...
7.
Pellatt A, Bhamidipati D, Subbiah V
JCO Oncol Pract
. 2024 May;
20(10):1289-1292.
PMID: 38739884
Understanding the landscape of KRAS mutations in #CRC is crucial with over 2.8M annual diagnoses worldwide. Explore promising therapies and ongoing challenges in this comprehensive review. #CancerResearch #KRAS #ColorectalCancer.
8.
Hornstein N, Zeineddine M, Gunes B, Pellatt A, Knafl M, Zhu H, et al.
Cancer Res Commun
. 2024 May;
4(5):1363-1368.
PMID: 38709066
Purpose: Appendiceal adenocarcinoma (AA) remains an orphan disease with limited treatment options for patients unable to undergo surgical resection. Evidence supporting the efficacy of combined VEGF and PD-1 inhibition in...
9.
Tian Y, Lin Y, Qu C, Arndt V, Baurley J, Berndt S, et al.
Br J Cancer
. 2024 Apr;
130(10):1687-1696.
PMID: 38561434
Background: Menopausal hormone therapy (MHT), a common treatment to relieve symptoms of menopause, is associated with a lower risk of colorectal cancer (CRC). To inform CRC risk prediction and MHT...
10.
Papadimitriou N, Qu C, Harrison T, Bever A, Martin R, Tsilidis K, et al.
EBioMedicine
. 2024 Feb;
101:105010.
PMID: 38350331
Background: Obesity has been positively associated with most molecular subtypes of colorectal cancer (CRC); however, the magnitude and the causality of these associations is uncertain. Methods: We used Mendelian randomization...