Andrew J McMichael
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Explore the profile of Andrew J McMichael including associated specialties, affiliations and a list of published articles.
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204
Citations
12025
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Recent Articles
1.
Gillespie G, Quastel M, McMichael A
Immunol Rev
. 2025 Jan;
329(1):e13434.
PMID: 39753525
HLA-E is a nonclassical, nonpolymorphic, class Ib HLA molecule. Its primary function is to present a conserved nonamer peptide, termed VL9, derived from the signal sequence of classical MHC molecules...
2.
Hwang J, Marston D, Wrapp D, Li D, Tuyishime M, Brackenridge S, et al.
bioRxiv
. 2024 Jul;
PMID: 39026709
One Sentence Summary: A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing by checkpoint inhibition and antibody dependent cellular cytotoxicity.
3.
Mosmann T, McMichael A, LeVert A, McCauley J, Almond J
Nat Rev Immunol
. 2024 May;
24(10):736-752.
PMID: 38698082
Vaccination remains our main defence against influenza, which causes substantial annual mortality and poses a serious pandemic threat. Influenza virus evades immunity by rapidly changing its surface antigens but, even...
4.
Brackenridge S, John N, Fruh K, Borrow P, McMichael A
Front Immunol
. 2024 Apr;
15:1329032.
PMID: 38571959
The commonly used antibodies 3D12 and 4D12 recognise the human leukocyte antigen E (HLA-E) protein. These antibodies bind distinct epitopes on HLA-E and differ in their ability to bind alleles...
5.
Huisman B, Guan N, Ruckert T, Garner L, Singh N, McMichael A, et al.
Nat Commun
. 2023 Aug;
14(1):5264.
PMID: 37644057
No abstract available.
6.
Huisman B, Guan N, Ruckert T, Garner L, Singh N, McMichael A, et al.
Nat Commun
. 2023 Aug;
14(1):4809.
PMID: 37558657
HLA-E is a non-classical class I MHC protein involved in innate and adaptive immune recognition. While recent studies have shown HLA-E can present diverse peptides to NK cells and T...
7.
Yang H, Sun H, Brackenridge S, Zhuang X, Wing P, Quastel M, et al.
Sci Immunol
. 2023 Jun;
8(84):eabl8881.
PMID: 37390223
Pathogen-specific CD8 T cell responses restricted by the nonpolymorphic nonclassical class Ib molecule human leukocyte antigen E (HLA-E) are rarely reported in viral infections. The natural HLA-E ligand is a...
8.
Lin Z, Bashirova A, Viard M, Garner L, Quastel M, Beiersdorfer M, et al.
Nat Immunol
. 2023 Jun;
24(7):1087-1097.
PMID: 37264229
Human leukocyte antigen (HLA)-E binds epitopes derived from HLA-A, HLA-B, HLA-C and HLA-G signal peptides (SPs) and serves as a ligand for CD94/NKG2A and CD94/NKG2C receptors expressed on natural killer...
9.
He W, Gea-Mallorqui E, Colin-York H, Fritzsche M, Gillespie G, Brackenridge S, et al.
J Exp Med
. 2023 May;
220(8).
PMID: 37140910
Interest in MHC-E-restricted CD8+ T cell responses has been aroused by the discovery of their efficacy in controlling simian immunodeficiency virus (SIV) infection in a vaccine model. The development of...
10.
Haynes B, Wiehe K, Borrow P, Saunders K, Korber B, Wagh K, et al.
Nat Rev Immunol
. 2023 Mar;
23(4):265.
PMID: 36859597
No abstract available.