Andrew I Perault
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Explore the profile of Andrew I Perault including associated specialties, affiliations and a list of published articles.
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10
Citations
134
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Recent Articles
1.
Perault A, John A, DuMont A, Shopsin B, Pironti A, Torres V
Proc Natl Acad Sci U S A
. 2025 Feb;
122(8):e2414315122.
PMID: 39977318
Pathogenic species are of increasing clinical concern due to the multidrug-resistant nature of these bacteria, including resistance to carbapenem antibiotics. Our understanding of virulence is limited, hindering the development of...
2.
Lubkin A, Bernard-Raichon L, DuMont A, Valero Jimenez A, Putzel G, Gago J, et al.
mBio
. 2024 Jul;
15(8):e0166724.
PMID: 39037272
Importance: The COVID-19 pandemic has had an enormous impact on healthcare across the globe. Patients who were severely infected with SARS-CoV-2, the virus causing COVID-19, sometimes became infected with other...
3.
Zhou C, Pawline M, Pironti A, Morales S, Perault A, Ulrich R, et al.
bioRxiv
. 2024 May;
PMID: 38766195
Depletion of microbiota increases susceptibility to gastrointestinal colonization and subsequent infection by opportunistic pathogens such as methicillin-resistant (MRSA). How the absence of gut microbiota impacts the evolution of MRSA is...
4.
Podkowik M, Perault A, Putzel G, Pountain A, Kim J, DuMont A, et al.
Elife
. 2024 Apr;
12.
PMID: 38687677
The quorum-sensing system links metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of HO, a crucial host defense against . We now report that...
5.
Podkowik M, Perault A, Putzel G, Pountain A, Kim J, DuMont A, et al.
bioRxiv
. 2023 Jun;
PMID: 37333372
The quorum-sensing system links metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of HO, a crucial host defense against . We now report that...
6.
John A, Perault A, Giacometti S, Sommerfield A, DuMont A, Lacey K, et al.
mBio
. 2023 Feb;
14(2):e0259022.
PMID: 36779722
Nosocomial infections caused by multidrug-resistant (MDR) Enterobacter cloacae complex (ECC) pathogens are on the rise. However, the virulence strategies employed by these pathogens remain elusive. Here, we study the interaction...
7.
Loeven N, Perault A, Cotter P, Hodges C, Schwartzman J, Hampton T, et al.
mBio
. 2021 Sep;
12(5):e0209821.
PMID: 34579569
Burkholderia cenocepacia is a member of the Burkholderia cepacia complex (Bcc), a group of bacteria with members responsible for causing lung infections in cystic fibrosis (CF) patients. The most severe...
8.
Perault A, Chandler C, Rasko D, Ernst R, Wolfgang M, Cotter P
Cell Host Microbe
. 2020 Aug;
28(4):534-547.e3.
PMID: 32755549
Pseudomonas aeruginosa and Burkholderia cepacia complex (Bcc) species are opportunistic lung pathogens of cystic fibrosis (CF) patients. While P. aeruginosa can initiate long-term infections in younger CF patients, Bcc infections...
9.
Perault A, Cotter P
J Bacteriol
. 2018 Aug;
200(22).
PMID: 30150233
The respiratory tracts of individuals afflicted with cystic fibrosis (CF) harbor complex polymicrobial communities. By an unknown mechanism, species of the Gram-negative complex, such as , can displace other bacteria...
10.
Bone M, Wilk A, Perault A, Marlatt S, Scheller E, Anthouard R, et al.
Proc Natl Acad Sci U S A
. 2017 Feb;
114(8):E1519-E1527.
PMID: 28167784
Bacterial pathogens coordinate virulence using two-component regulatory systems (TCS). The virulence gene (BvgAS) phosphorelay-type TCS controls expression of all known protein virulence factor-encoding genes and is considered the "master virulence...