Andrew H Limper
Overview
Explore the profile of Andrew H Limper including associated specialties, affiliations and a list of published articles.
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213
Citations
4714
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Recent Articles
1.
Pellegrino M, Bindzus M, Kottom T, Ayyalasomayajula S, Yi E, Limper A
bioRxiv
. 2025 Jan;
PMID: 39829820
Background And Objective: Previously, the novel small molecule ISFP10 has been shown to inhibit fungal phosphoglucomutase (PGM) activity in and spp. With 50-fold selectivity over the human PGM molecule due...
2.
Kottom T, Carmona E, Schaefbauer K, Stelzig K, Pellegrino M, Bindzus M, et al.
Infect Immun
. 2025 Jan;
93(2):e0027624.
PMID: 39745390
pneumonia (PJP) remains a significant cause of morbidity and mortality during AIDS. In AIDS, the absence of CD4 immunity results in exuberant and often fatal PJP. In addition, organism clearance...
3.
Epelbaum O, Marinelli T, Haydour Q, Pennington K, Evans S, Carmona E, et al.
Am J Respir Crit Care Med
. 2024 Nov;
PMID: 39556361
Background: The incidence of invasive fungal infections is increasing in immune-competent and immune-compromised patients. An examination of the recent literature related to the treatment of fungal infections was performed to...
4.
Limper A, Thao V, Helfinstine D, Sangaralingham L, Dempsey T
Chest
. 2024 Oct;
167(3):800-805.
PMID: 39368738
No abstract available.
5.
Kottom T, Stelzig K, Pellegrino M, Bindzus M, Yi E, Limper A
Drugs R D
. 2024 Aug;
24(3):425-434.
PMID: 39105996
Background And Objective: The EphA2 receptor inhibitor ALW-II-41-27 has proven to be an effective in vitro antagonist of Pneumocystis β-glucan-induced proinflammatory signaling. This suggests its potential as a candidate for...
6.
Kottom T, Carmona E, Lepenies B, Limper A
Cell Surf
. 2024 Jul;
11:100123.
PMID: 39022598
Herein, this manuscript explores the significance of the phosphoglucomutase (PGM) enzyme in spp., focusing on its role in fungal surface mannoprotein formation. Through expression of the in a strain, we...
7.
Kanj A, Guiance I, Kottom T, Schaefbauer K, Choudhury M, Limper A, et al.
Med Mycol
. 2024 Feb;
62(2).
PMID: 38331424
Overgrowth of the fungus Wallemia mellicola in the intestines of mice enhances the severity of asthma. Wallemia mellicola interacts with the immune system through Dectin-2 expressed on the surface of...
8.
Kottom T, Carmona E, Limper A
Antimicrob Agents Chemother
. 2024 Jan;
68(3):e0075623.
PMID: 38259086
cyst life forms contain abundant β-glucan carbohydrates, synthesized using β-1,3 and β-1,6 glucan synthase enzymes and the donor uridine diphosphate (UDP)-glucose. In yeast, phosphoglucomutase (PGM) plays a crucial role in...
9.
Kottom T, Carmona E, Limper A
Antimicrob Agents Chemother
. 2024 Jan;
68(2):e0081123.
PMID: 38206037
the fungus that causes pneumonia (PJP), is a leading cause of morbidity and mortality in immunocompromised individuals. We have previously shown that lung epithelial cells can bind spp. β-glucans via...
10.
Yadav H, Hefazi Torghabeh M, Hogan W, Limper A
CHEST Pulm
. 2023 Oct;
1(2).
PMID: 37814644
No abstract available.