Andrew G Sprague
Overview
Explore the profile of Andrew G Sprague including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
413
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0
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Recent Articles
1.
Kusner L, Yucius K, Sengupta M, Sprague A, Desai D, Nguyen T, et al.
Mol Ther Methods Clin Dev
. 2019 Jun;
13:484-492.
PMID: 31193726
Complement-mediated damage to the neuromuscular junction (NMJ) is a key mechanism of pathology in myasthenia gravis (MG) and therapeutics inhibiting complement have shown evidence of efficacy in the treatment of...
2.
Ramishetti S, Kedmi R, Goldsmith M, Leonard F, Sprague A, Godin B, et al.
ACS Nano
. 2015 Jun;
9(7):6706-16.
PMID: 26042619
Modulating T cell function by down-regulating specific genes using RNA interference (RNAi) holds tremendous potential in advancing targeted therapies in many immune-related disorders including cancer, inflammation, autoimmunity, and viral infections....
3.
Weinstein S, Emmanuel R, Jacobi A, Abraham A, Behlke M, Sprague A, et al.
PLoS One
. 2012 Aug;
7(8):e43343.
PMID: 22905260
Mantle cell lymphoma is characterized by a genetic translocation results in aberrant overexpression of the CCND1 gene, which encodes cyclin D1. This protein functions as a regulator of the cell...
4.
Ray S, Franki S, Pierce R, Dimitrova S, Koteliansky V, Sprague A, et al.
Immunity
. 2004 Feb;
20(2):167-79.
PMID: 14975239
A common feature of many infections is that many pathogen-specific memory T cells become established in diverse nonlymphoid tissues. A mechanism that promotes the retention and survival of the memory...
5.
Andreasen S, Thomsen A, Koteliansky V, Novobrantseva T, Sprague A, de Fougerolles A, et al.
J Immunol
. 2003 Sep;
171(6):2804-11.
PMID: 12960301
Adhesive interactions are crucial to cell migration into inflammatory sites. Using murine lymphocytic choriomeningitis virus as an Ag model system, we have investigated expression and function of collagen-binding integrins, alpha(1)beta(1)...
6.
Krieglstein C, Cerwinka W, Sprague A, Laroux F, Grisham M, Koteliansky V, et al.
J Clin Invest
. 2002 Dec;
110(12):1773-82.
PMID: 12488427
Central to inflammatory responses are the integrin-mediated adhesive interactions of cells with their ECM-rich environment. We investigated the role of the collagen-binding integrin alpha(1)beta(1) in intestinal inflammation using the mouse...
7.
Fiorucci S, Mencarelli A, Palazzetti B, Sprague A, Distrutti E, Morelli A, et al.
Immunity
. 2002 Dec;
17(6):769-80.
PMID: 12479823
Inflammation occurs in the context of integrin-mediated adhesive interactions of cells with their extracellular matrix environment. We investigated the role of the collagen binding integrin alpha1beta1 in a model of...