Andrew Dunham
Overview
Explore the profile of Andrew Dunham including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
15
Citations
1483
Followers
0
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Related Specialties
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Recent Articles
1.
Reikvam H, Hetland G, Ezligini F, Dorsch K, Omert L, Dunham A, et al.
Transfus Apher Sci
. 2023 Jul;
62(5):103755.
PMID: 37423867
Anemia is a common symptom of hematological malignancies and red blood cell (RBC) transfusion is the primary supportive treatment, with many patients becoming transfusion dependent. Hemanext Inc. (Lexington, MA, United...
2.
Bencheikh L, Nguyen K, Chadebech P, Kiger L, Bodivit G, Jouard A, et al.
Haematologica
. 2022 Mar;
107(8):1944-1949.
PMID: 35354249
No abstract available.
3.
Yoshida T, McMahon E, Croxon H, Dunham A, Gaccione P, Abbasi B, et al.
Transfusion
. 2021 Nov;
62(1):183-193.
PMID: 34761414
Background: Oxidative stress is a major driving force in the development of storage lesions in red cell concentrates (RCCs). Unlike manufactured pharmaceuticals, differences in component preparation methods and genetic/physiological status...
4.
Bardyn M, Martin A, Dognitz N, Abonnenc M, Dunham A, Yoshida T, et al.
Front Physiol
. 2021 Jan;
11:616457.
PMID: 33424640
Unexpectedly wide distribution (<10 to >90%) of hemoglobin oxygen saturation (sO) within red cell concentrates (RCCs) has recently been observed. Causes of such variability are not yet completely explained whereas...
5.
Bardyn M, Crettaz D, Borlet M, Langst E, Martin A, Abonnenc M, et al.
Blood Transfus
. 2020 Sep;
19(4):300-308.
PMID: 32955427
Background: γ-irradiation is used to treat red blood cell (RBC) concentrates (RCCs) transfused to immunosuppressed patients. This treatment damages RBCs and increases storage lesions. Several studies have shown the beneficial...
6.
DAlessandro A, Yoshida T, Nestheide S, Nemkov T, Stocker S, Stefanoni D, et al.
Transfusion
. 2020 Feb;
60(4):786-798.
PMID: 32104927
Background: Blood transfusion is a lifesaving intervention for millions of recipients worldwide every year. Storing blood makes this possible but also promotes a series of alterations to the metabolism of...
7.
Williams A, Jani V, Nemkov T, Lucas A, Yoshida T, Dunham A, et al.
Shock
. 2019 Sep;
53(3):352-362.
PMID: 31478989
Background: Resuscitation from hemorrhagic shock (HS) by blood transfusion restores oxygen (O2) delivery and provides hemodynamic stability. Current regulations allow red blood cells (RBCs) to be stored and used for...
8.
Reisz J, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill R, et al.
Transfusion
. 2018 Oct;
58(12):2978-2991.
PMID: 30312994
Background: Being devoid of de novo protein synthesis capacity, red blood cells (RBCs) have evolved to recycle oxidatively damaged proteins via mechanisms that involve methylation of dehydrated and deamidated aspartate...
9.
Nemkov T, Sun K, Reisz J, Yoshida T, Dunham A, Wen E, et al.
Front Med (Lausanne)
. 2017 Nov;
4:175.
PMID: 29090212
State-of-the-art proteomics technologies have recently helped to elucidate the unanticipated complexity of red blood cell metabolism. One recent example is citrate metabolism, which is catalyzed by cytosolic isoforms of Krebs...
10.
Nemkov T, Sun K, Reisz J, Song A, Yoshida T, Dunham A, et al.
Haematologica
. 2017 Oct;
103(2):361-372.
PMID: 29079593
Hypoxanthine catabolism is potentially dangerous as it fuels production of urate and, most importantly, hydrogen peroxide. However, it is unclear whether accumulation of intracellular and supernatant hypoxanthine in stored red...