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Andrew Chandler

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Citations 88
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Recent Articles
1.
Chakafana G, Boswell R, Chandler A, Jackson K, Neblett S, Postal T, et al.
Acta Crystallogr F Struct Biol Commun . 2024 Aug; 80(Pt 9):193-199. PMID: 39177244
Brucella ovis is an etiologic agent of ovine epididymitis and brucellosis that causes global devastation in sheep, rams, goats, small ruminants and deer. There are no cost-effective methods for the...
2.
Fujiwara T, Zhang L, Chandler A, Sung S, Yakoub M, Linkov I, et al.
Hum Pathol . 2022 Dec; 134:30-44. PMID: 36565726
Cathepsin proteases, activated in the lysosomes, are upregulated in many cancers. Intraoperative detection systems of microscopic residual tumor using cathepsin-mediated release of fluorescent nanoparticles may guide surgical excisions to improve...
3.
Abdulrazzak A, Chandler A, Lu R, Mobarakai O, Lebron B, Ingram N, et al.
J Osteopath Med . 2021 Oct; 121(12):883-890. PMID: 34668364
Context: The percent of underrepresented minority (URM) students who apply to medical school has changed minimally in the past 40 years. Due to the lack of URM applicants, the consequent...
4.
Fujiwara T, Yakoub M, Chandler A, Christ A, Yang G, Ouerfelli O, et al.
Mol Cancer Ther . 2021 Jun; 20(8):1388-1399. PMID: 34088832
Colony-stimulating factor 1 (CSF1) is a primary regulator of the survival, proliferation, and differentiation of monocyte/macrophage that sustains the protumorigenic functions of tumor-associated macrophages (TAMs). Considering current advances in understanding...
5.
Chandler A, Bartelstein M, Fujiwara T, Antonescu C, Healey J, Vaynrub M
BMC Musculoskelet Disord . 2021 Apr; 22(1):320. PMID: 33794838
Background: Giant cell tumor of bone is a benign, locally aggressive neoplasm. Surgical resection is the preferred treatment method. However, for cases in which resection poses an increased risk to...
6.
Anderson S, Tabassum A, Yeon J, Sharma G, Santos P, Soong T, et al.
PLoS Comput Biol . 2020 Nov; 16(11):e1007719. PMID: 33237899
Angiotensin II type 1 receptor (AT1R) blockers (ARBs) are among the most prescribed drugs. However, ARB effectiveness varies widely, which may be due to non-synonymous single nucleotide polymorphisms (nsSNPs) within...
7.
Heitzinger K, Thoroughman D, Johnson B, Chandler A, Prather J, Walls H, et al.
Disaster Med Public Health Prep . 2020 Apr; 15(2):160-163. PMID: 32321613
Objective: The 2017 solar eclipse was associated with mass gatherings in many of the 14 states along the path of totality. The Kentucky Department for Public Health implemented an enhanced...