Andrew C Jamieson
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Explore the profile of Andrew C Jamieson including associated specialties, affiliations and a list of published articles.
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10
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1032
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Recent Articles
1.
Cradick T, Keck K, Bradshaw S, Jamieson A, McCaffrey A
Mol Ther
. 2010 Feb;
18(5):947-54.
PMID: 20160705
Hepatitis B virus (HBV) chronically infects 350-400 million people worldwide and causes >1 million deaths yearly. Current therapies prevent new viral genome formation, but do not target pre-existing viral genomic...
2.
Reik A, Zhou Y, Collingwood T, Warfe L, Bartsevich V, Kong Y, et al.
Biotechnol Bioeng
. 2006 Dec;
97(5):1180-9.
PMID: 17171718
Increasing the yield of therapeutic proteins from mammalian production cell lines reduces costs and decreases the time to market. To this end, we engineered a zinc finger protein transcription factor...
3.
Controlling gene expression in Drosophila using engineered zinc finger protein transcription factors
Jamieson A, Guan B, Cradick T, Xiao H, Holmes M, Gregory P, et al.
Biochem Biophys Res Commun
. 2006 Aug;
348(3):873-9.
PMID: 16899226
Zinc finger protein transcription factors (ZFP TFs) have been designed to control the expression of endogenous genes in a variety of cells. However, thus far the use of engineered ZFP...
4.
Holmes-Davis R, Li G, Jamieson A, Rebar E, Liu Q, Kong Y, et al.
Plant Mol Biol
. 2005 Apr;
57(3):411-23.
PMID: 15830130
The ability to modify plant traits is of great commercial potential in agricultural biotechnology. To this end we have engineered plant-based zinc finger protein transcription factors (ZFP TFs) that minimize...
5.
Urnov F, Miller J, Lee Y, Beausejour C, Rock J, Augustus S, et al.
Nature
. 2005 Apr;
435(7042):646-51.
PMID: 15806097
Permanent modification of the human genome in vivo is impractical owing to the low frequency of homologous recombination in human cells, a fact that hampers biomedical research and progress towards...
6.
Van Eenennaam A, Li G, Venkatramesh M, Levering C, Gong X, Jamieson A, et al.
Metab Eng
. 2004 Apr;
6(2):101-8.
PMID: 15113563
Synthetic zinc finger transcription factors (ZFP-TFs) were designed to upregulate the expression of the endogenous Arabidopsis gamma-tocopherol methyltransferase (GMT) gene. This gene encodes the enzyme responsible for the conversion of...
7.
Snowden A, Zhang L, Urnov F, Dent C, Jouvenot Y, Zhong X, et al.
Cancer Res
. 2003 Dec;
63(24):8968-76.
PMID: 14695215
Angiogenic factors are necessary for tumor proliferation and thus are attractive therapeutic targets. In this study, we have used engineered zinc finger protein (ZFP) transcription factors (TFs) to repress expression...
8.
9.
Jamieson A, Miller J, Pabo C
Nat Rev Drug Discov
. 2003 May;
2(5):361-8.
PMID: 12750739
Zinc-finger proteins (ZFPs) that recognize novel DNA sequences are the basis of a powerful technology platform with many uses in drug discovery and therapeutics. These proteins have been used as...
10.
Rebar E, Huang Y, Hickey R, Nath A, Meoli D, Nath S, et al.
Nat Med
. 2002 Nov;
8(12):1427-32.
PMID: 12415262
The relationship between the structure of zinc-finger protein (ZFP) transcription factors and DNA sequence binding specificity has been extensively studied. Advances in this field have made it possible to design...