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Andrew Beppu

Explore the profile of Andrew Beppu including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 12
Citations 372
Followers 0
Related Specialty
Allergy & Immunology
Top 10 Co-Authors
Marina Miller
Peter Rosenthal
David H Broide
Sudipta Das
Taylor A Doherty
Michael Croft
Christine Vuong
Hal M Hoffman
Richard C Kurten
Maho Niwa
Published In
J Allergy Clin Immunol
J Immunol
Front Immunol
J Pediatr Gastroenterol Nutr
Affiliations
Soon will be listed here.
Recent Articles
1.
Macrophage MMP10 Regulates TLR7-Mediated Tolerance
Rohani M, Dimitrova E, Beppu A, Wang Y, Jefferies C, Parks W
Front Immunol . 2018 Dec; 9:2817. PMID: 30564235
Using an model of tolerance to TLR7-induced skin inflammation, we found a critical role for macrophage-derived MMP10 in mediating immune hypo-responsiveness. Cutaneous exposure to Imiquimod (IMQ), a TLR7 agonist, induced...
2.
Activating transcription factor 6α (ATF6α) regulates airway hyperreactivity, smooth muscle proliferation, and contractility
Unno H, Miller M, Rosenthal P, Beppu A, Das S, Broide D
J Allergy Clin Immunol . 2017 Sep; 141(1):439-442.e4. PMID: 28958904
No abstract available.
3.
Rhinovirus Infection of ORMDL3 Transgenic Mice Is Associated with Reduced Rhinovirus Viral Load and Airway Inflammation
Song D, Miller M, Beppu A, Rosenthal P, Das S, Karta M, et al.
J Immunol . 2017 Aug; 199(7):2215-2224. PMID: 28827284
Orosomucoid like 3 (ORMDL3), a gene localized to chromosome 17q21, has been linked in epidemiologic studies to childhood asthma and rhinovirus (RV) infections. As the single nucleotide polymorphisms linking ORMDL3...
4.
β integrins rather than β integrins mediate Alternaria-induced group 2 innate lymphoid cell trafficking to the lung
Karta M, Rosenthal P, Beppu A, Vuong C, Miller M, Das S, et al.
J Allergy Clin Immunol . 2017 Apr; 141(1):329-338.e12. PMID: 28366795
Background: Group 2 innate lymphoid cells (ILC2s) expand in the lungs of mice during type 2 inflammation induced by the fungal allergen Alternaria alternata. The increase in ILC2 numbers in...
5.
Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate
Miller M, Tam A, Mueller J, Rosenthal P, Beppu A, Gordillo R, et al.
J Immunol . 2017 Mar; 198(8):3017-3022. PMID: 28275141
In this study, we used cre-lox techniques to generate mice selectively deficient in ORMDL3 in airway epithelium () to simulate an inhaled therapy that effectively inhibited ORMDL3 expression in the...
6.
Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide
Miller M, Rosenthal P, Beppu A, Gordillo R, Broide D
J Allergy Clin Immunol . 2016 Nov; 139(4):1373-1376.e4. PMID: 27826095
No abstract available.
7.
Regulatory B cells and T follicular helper cells are reduced in allergic rhinitis
Kim A, Doherty T, Karta M, Das S, Baum R, Rosenthal P, et al.
J Allergy Clin Immunol . 2016 May; 138(4):1192-1195.e5. PMID: 27142393
No abstract available.
8.
Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma
Miller M, Esnault S, Kurten R, Kelly E, Beppu A, Das S, et al.
J Allergy Clin Immunol . 2016 Mar; 138(2):596-599.e4. PMID: 27001159
No abstract available.
9.
Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M
Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, et al.
J Immunol . 2015 Sep; 195(8):3546-56. PMID: 26355153
Chronic asthma is associated with airway remodeling and decline in lung function. In this article, we show that follistatin-like 1 (Fstl1), a mediator not previously associated with asthma, is highly...
10.
ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma
Miller M, Rosenthal P, Beppu A, Mueller J, Hoffman H, Tam A, et al.
J Immunol . 2014 Mar; 192(8):3475-87. PMID: 24623133
Orosomucoid-like (ORMDL)3 has been strongly linked with asthma in genetic association studies. Because allergen challenge induces lung ORMDL3 expression in wild-type mice, we have generated human ORMDL3 zona pellucida 3...