Andrew B Sparks
Overview
Explore the profile of Andrew B Sparks including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
3077
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0
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Recent Articles
1.
Morin P, Kinzler K, Sparks A
Cancer Res
. 2016 Oct;
76(19):5587-5589.
PMID: 27698186
No abstract available.
2.
Peters B, Kermani B, Sparks A, Alferov O, Hong P, Alexeev A, et al.
Nature
. 2012 Jul;
487(7406):190-5.
PMID: 22785314
Recent advances in whole-genome sequencing have brought the vision of personal genomics and genomic medicine closer to reality. However, current methods lack clinical accuracy and the ability to describe the...
3.
Norton M, Brar H, Weiss J, Karimi A, Laurent L, Caughey A, et al.
Am J Obstet Gynecol
. 2012 Jun;
207(2):137.e1-8.
PMID: 22742782
Objective: We sought to evaluate performance of a noninvasive prenatal test for fetal trisomy 21 (T21) and trisomy 18 (T18). Study Design: A multicenter cohort study was performed whereby cell-free...
4.
Sparks A, Struble C, Wang E, Song K, Oliphant A
Am J Obstet Gynecol
. 2012 Apr;
206(4):319.e1-9.
PMID: 22464072
Objective: We sought to develop a novel biochemical assay and algorithm for the prenatal evaluation of risk for fetal trisomy 21 (T21) and trisomy 18 (T18) using cell-free DNA obtained...
5.
Sparks A, Wang E, Struble C, Barrett W, Stokowski R, McBride C, et al.
Prenat Diagn
. 2012 Jan;
32(1):3-9.
PMID: 22223233
Objective: To develop a novel prenatal assay based on selective analysis of cell-free DNA in maternal blood for evaluation of fetal Trisomy 21 (T21) and Trisomy 18 (T18). Methods: Two...
6.
Lee W, Jiang Z, Liu J, Haverty P, Guan Y, Stinson J, et al.
Nature
. 2010 May;
465(7297):473-7.
PMID: 20505728
Lung cancer is the leading cause of cancer-related mortality worldwide, with non-small-cell lung carcinomas in smokers being the predominant form of the disease. Although previous studies have identified important common...
7.
Drmanac R, Sparks A, Callow M, Halpern A, Burns N, Kermani B, et al.
Science
. 2009 Nov;
327(5961):78-81.
PMID: 19892942
Genome sequencing of large numbers of individuals promises to advance the understanding, treatment, and prevention of human diseases, among other applications. We describe a genome sequencing platform that achieves efficient...
8.
Wood L, Parsons D, Jones S, Lin J, Sjoblom T, Leary R, et al.
Science
. 2007 Oct;
318(5853):1108-13.
PMID: 17932254
Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalog the genetic changes that occur during tumorigenesis, we isolated DNA from 11 breast...
9.
Saha S, Sparks A, Rago C, Akmaev V, Wang C, Vogelstein B, et al.
Nat Biotechnol
. 2002 May;
20(5):508-12.
PMID: 11981567
A remaining challenge for the human genome project involves the identification and annotation of expressed genes. The public and private sequencing efforts have identified approximately 15,000 sequences that meet stringent...