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Bahram G Kermani

Explore the profile of Bahram G Kermani including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 1453
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Recent Articles
1.
Dong Z, Zhao X, Li Q, Yang Z, Xi Y, Alexeev A, et al.
DNA Res . 2019 Jun; 26(4):313-325. PMID: 31173071
The diversity of disease presentations warrants one single assay for detection and delineation of various genomic disorders. Herein, we describe a gel-free and biotin-capture-free mate-pair method through coupling Controlled Polymerizations...
2.
Kermani B
Per Med . 2018 May; 13(4):287-290. PMID: 29749808
Crystal Genetics, Inc. is an early-stage genetic test company, focused on achieving the highest possible clinical-grade accuracy and comprehensiveness for detecting germline (e.g., in hereditary cancer) and somatic (e.g., in...
3.
Lanman R, Mortimer S, Zill O, Sebisanovic D, Lopez R, Blau S, et al.
PLoS One . 2015 Oct; 10(10):e0140712. PMID: 26474073
Next-generation sequencing of cell-free circulating solid tumor DNA addresses two challenges in contemporary cancer care. First this method of massively parallel and deep sequencing enables assessment of a comprehensive panel...
4.
Peters B, Kermani B, Alferov O, Agarwal M, McElwain M, Gulbahce N, et al.
Genome Res . 2015 Feb; 25(3):426-34. PMID: 25672852
Currently, the methods available for preimplantation genetic diagnosis (PGD) of in vitro fertilized (IVF) embryos do not detect de novo single-nucleotide and short indel mutations, which have been shown to...
5.
Peters B, Kermani B, Sparks A, Alferov O, Hong P, Alexeev A, et al.
Nature . 2012 Jul; 487(7406):190-5. PMID: 22785314
Recent advances in whole-genome sequencing have brought the vision of personal genomics and genomic medicine closer to reality. However, current methods lack clinical accuracy and the ability to describe the...
6.
Drmanac R, Sparks A, Callow M, Halpern A, Burns N, Kermani B, et al.
Science . 2009 Nov; 327(5961):78-81. PMID: 19892942
Genome sequencing of large numbers of individuals promises to advance the understanding, treatment, and prevention of human diseases, among other applications. We describe a genome sequencing platform that achieves efficient...
7.
Kozlov I, Kermani B, Melnyk P, Barker D, Zhao C, Hachmann J, et al.
J Chromatogr Sci . 2007 May; 45(4):207-11. PMID: 17504569
The retention of histidine-containing peptides in immobilized metal-affinity chromatography is studied using several hundred modeled peptides. Retention is driven primarily by the number of histidine residues; however, the amino acid...
8.
Shults M, Kozlov I, Nelson N, Kermani B, Melnyk P, Shevchenko V, et al.
Chembiochem . 2007 May; 8(8):933-42. PMID: 17471478
We report a novel protein kinase assay designed for high-throughput detection of one or many kinases in a complex mixture. A solution-phase phosphorylation reaction is performed on 900 different peptide...
9.
Shen R, Fan J, Campbell D, Chang W, Chen J, Doucet D, et al.
Mutat Res . 2005 Apr; 573(1-2):70-82. PMID: 15829238
We have developed a flexible, accurate and highly multiplexed SNP genotyping assay for high-throughput genetic analysis of large populations on a bead array platform. The novel genotyping system combines high...
10.
Murray S, Oliphant A, Shen R, McBride C, Steeke R, Shannon S, et al.
Nat Methods . 2005 Mar; 1(2):113-7. PMID: 15782173
We have developed a highly informative set of single-nucleotide polymorphism (SNP) assays designed for linkage mapping of the human genome. These assays were developed on a robust multiplexed assay system...