Andrew B Knott
Overview
Explore the profile of Andrew B Knott including associated specialties, affiliations and a list of published articles.
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7
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949
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Recent Articles
1.
Kaliszewski M, Kennedy A, Blaes S, Shaffer R, Knott A, Song W, et al.
Front Cell Neurosci
. 2017 Jan;
10:287.
PMID: 28066183
Superoxide dismutase 1 (SOD1) knockout () mice exhibit an accelerated aging phenotype. In humans, mutations are linked to familial amyotrophic lateral sclerosis (ALS), and post-translational modification (PTM) of wild-type SOD1...
2.
Bossy B, Petrilli A, Klinglmayr E, Chen J, Lutz-Meindl U, Knott A, et al.
J Alzheimers Dis
. 2010 May;
20 Suppl 2:S513-26.
PMID: 20463395
Mitochondrial dysfunction and synaptic loss are among the earliest events linked to Alzheimer's disease (AD) and might play a causative role in disease onset and progression. The underlying mechanisms of...
3.
Knott A, Bossy-Wetzel E
Ann N Y Acad Sci
. 2008 Dec;
1147:283-92.
PMID: 19076450
Mitochondrial dysfunction is a common characteristic of all neurodegenerative diseases. However, the cause of this dysfunction remains a mystery. Here, we discuss the potential role of mitochondrial fission and fusion...
4.
Song W, Bossy B, Martin O, Hicks A, Lubitz S, Knott A, et al.
Methods
. 2008 Oct;
46(4):295-303.
PMID: 18952177
Mitochondrial morphology and length change during fission and fusion and mitochondrial movement varies dependent upon the cell type and the physiological conditions. Here, we describe fundamental wide-field fluorescence microscopy and...
5.
Bossy-Wetzel E, Petrilli A, Knott A
Trends Neurosci
. 2008 Oct;
31(12):609-16.
PMID: 18951640
Huntington's disease (HD) is a fatal, inherited neurodegenerative disorder that gradually robs affected individuals of memory, cognitive skills and normal movements. Although research has identified a single faulty gene, the...
6.
Knott A, Bossy-Wetzel E
Antioxid Redox Signal
. 2008 Aug;
11(3):541-54.
PMID: 18715148
Nitric oxide (NO) is an important messenger molecule in a variety of physiological systems. NO, a gas, is produced from L-arginine by different isoforms of nitric oxide synthase (NOS) and...
7.
Knott A, Perkins G, Schwarzenbacher R, Bossy-Wetzel E
Nat Rev Neurosci
. 2008 Jun;
9(7):505-18.
PMID: 18568013
Mitochondria are remarkably dynamic organelles that migrate, divide and fuse. Cycles of mitochondrial fission and fusion ensure metabolite and mitochondrial DNA mixing and dictate organelle shape, number and bioenergetic functionality....