Andrew A Augustine
Overview
Explore the profile of Andrew A Augustine including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
107
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Recent Articles
1.
Burns G, Hilal O, Sun Z, Reutter K, Preston G, Augustine A, et al.
FEBS Lett
. 2021 Aug;
595(18):2383-2394.
PMID: 34358326
Maintenance of the proteome (proteostasis) is essential for cellular homeostasis and prevents cytotoxic stress responses that arise from protein misfolding. However, little is known about how different types of misfolded...
2.
Guerriero C, Gomez Y, Daskivich G, Reutter K, Augustine A, Weiberth K, et al.
Biophys J
. 2019 Aug;
117(4):668-678.
PMID: 31399214
Membrane proteins must adopt their proper topologies within biological membranes, but achieving the correct topology is compromised by the presence of marginally hydrophobic transmembrane helices (TMHs). In this study, we...
3.
Hager N, Krasowski C, Mackie T, Kolb A, Needham P, Augustine A, et al.
J Biol Chem
. 2018 May;
293(28):11006-11021.
PMID: 29784874
Protein composition at the plasma membrane is tightly regulated, with rapid protein internalization and selective targeting to the cell surface occurring in response to environmental changes. For example, ion channels...
4.
Guerriero C, Reutter K, Augustine A, Preston G, Weiberth K, Mackie T, et al.
Mol Biol Cell
. 2017 May;
28(15):2076-2090.
PMID: 28539401
Integral membrane proteins fold inefficiently and are susceptible to turnover via the endoplasmic reticulum-associated degradation (ERAD) pathway. During ERAD, misfolded proteins are recognized by molecular chaperones, polyubiquitinated, and retrotranslocated to...
5.
Alvaro C, ODonnell A, Prosser D, Augustine A, Goldman A, Brodsky J, et al.
Mol Cell Biol
. 2014 May;
34(14):2660-81.
PMID: 24820415
G-protein-coupled receptors (GPCRs) are integral membrane proteins that initiate responses to extracellular stimuli by mediating ligand-dependent activation of cognate heterotrimeric G proteins. In yeast, occupancy of GPCR Ste2 by peptide...