Andreia M Gomes
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Explore the profile of Andreia M Gomes including associated specialties, affiliations and a list of published articles.
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5
Citations
105
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Recent Articles
1.
Silverio-Alves R, Gomes A, Kurochkin I, Moore K, Pereira C
J Vis Exp
. 2019 Nov;
(153).
PMID: 31736500
The cellular and molecular mechanisms underlying specification of human hematopoietic stem cells (HSCs) remain elusive. Strategies to recapitulate human HSC emergence in vitro are required to overcome limitations in studying...
2.
Daniel M, Sachs D, Bernitz J, Fstkchyan Y, Rapp K, Satija N, et al.
FEBS Lett
. 2019 Sep;
593(23):3266-3287.
PMID: 31557312
Transcription factor (TF)-based reprogramming of somatic tissues holds great promise for regenerative medicine. Previously, we demonstrated that the TFs GATA2, GFI1B, and FOS convert mouse and human fibroblasts to hemogenic...
3.
Rosa F, Pires C, Kurochkin I, Ferreira A, Gomes A, Palma L, et al.
Sci Immunol
. 2018 Dec;
3(30).
PMID: 30530727
Ectopic expression of transcription factors has been used to reprogram differentiated somatic cells toward pluripotency or to directly reprogram them to other somatic cell lineages. This concept has been explored...
4.
Gomes A, Kurochkin I, Chang B, Daniel M, Law K, Satija N, et al.
Cell Rep
. 2018 Dec;
25(10):2821-2835.e7.
PMID: 30517869
During development, hematopoietic stem and progenitor cells (HSPCs) arise from specialized endothelial cells by a process termed endothelial-to-hematopoietic transition (EHT). The genetic program driving human HSPC emergence remains largely unknown....
5.
Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism
Kim H, Yoo S, Zhou R, Xu A, Bernitz J, Yuan Y, et al.
Proc Natl Acad Sci U S A
. 2018 Nov;
115(47):E11128-E11137.
PMID: 30385632
Osteosarcoma (OS), the most common primary bone tumor, is highly metastatic with high chemotherapeutic resistance and poor survival rates. Using induced pluripotent stem cells (iPSCs) generated from Li-Fraumeni syndrome (LFS)...