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Andrei Kuzmichev

Explore the profile of Andrei Kuzmichev including associated specialties, affiliations and a list of published articles. Areas
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Citations 1392
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Recent Articles
1.
Kuzmichev A, Margueron R, Vaquero A, Preissner T, Scher M, Kirmizis A, et al.
Proc Natl Acad Sci U S A . 2005 Feb; 102(6):1859-64. PMID: 15684044
Changes in the substrate specificities of factors that irreversibly modify the histone components of chromatin are expected to have a profound effect on gene expression through epigenetics. Ezh2 is a...
2.
Kirmizis A, Bartley S, Kuzmichev A, Margueron R, Reinberg D, Green R, et al.
Genes Dev . 2004 Jul; 18(13):1592-605. PMID: 15231737
Polycomb group (PcG) complexes 2 and 3 are involved in transcriptional silencing. These complexes contain a histone lysine methyltransferase (HKMT) activity that targets different lysine residues on histones H1 or...
3.
Kuzmichev A, Jenuwein T, Tempst P, Reinberg D
Mol Cell . 2004 Apr; 14(2):183-93. PMID: 15099518
Human Enhancer of Zeste homolog (Ezh2) is a histone lysine methyltransferase (HKMT) associated with transcriptional repression. Ezh2 is present in several distinct complexes, one of which, PRC2, we characterized previously....
4.
Kuzmichev A, Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D
Genes Dev . 2002 Nov; 16(22):2893-905. PMID: 12435631
Enhancer of Zeste [E(z)] is a Polycomb-group transcriptional repressor and one of the founding members of the family of SET domain-containing proteins. Several SET-domain proteins possess intrinsic histone methyltransferase (HMT)...