Andreas Schlundt
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Explore the profile of Andreas Schlundt including associated specialties, affiliations and a list of published articles.
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51
Citations
790
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Recent Articles
1.
Mertinkus K, Oxenfarth A, Richter C, Wacker A, Mata C, Carazo J, et al.
J Am Chem Soc
. 2025 Feb;
147(8):7158.
PMID: 39937987
No abstract available.
2.
Ceylan B, Adam J, Toews S, Kaiser F, Dorr J, Scheppa D, et al.
Angew Chem Int Ed Engl
. 2025 Jan;
64(9):e202417961.
PMID: 39887818
Targeting the RNA genome of SARS-CoV-2 is a viable option for antiviral drug development. We explored three ligand binding sites of the core pseudoknot RNA of the SARS-CoV-2 frameshift element....
3.
Tants J, Friedrich K, Neumann J, Schlundt A
RNA Biol
. 2025 Jan;
22(1):1-12.
PMID: 39801464
RNA elements play pivotal roles in regulatory processes, e.g. in transcriptional and translational regulation. Two stem-looped elements, the constitutive and alternative decay elements (CDE and ADE, respectively) are shape-specifically recognized...
4.
Dhamotharan K, Korn S, Wacker A, Becker M, Gunther S, Schwalbe H, et al.
Nat Commun
. 2024 Dec;
15(1):10656.
PMID: 39653699
The SARS-CoV-2 nucleocapsid protein is indispensable for viral RNA genome processing. Although the N-terminal domain (NTD) is suggested to mediate specific RNA-interactions, high-resolution structures with viral RNA are still lacking....
5.
Sieber A, Parr M, von Ehr J, Dhamotharan K, Kielkowski P, Brewer T, et al.
Nat Commun
. 2024 Dec;
15(1):10465.
PMID: 39622818
Polyproline sequences are deleterious to cells because they stall ribosomes. In bacteria, EF-P plays an important role in overcoming such polyproline sequence-induced ribosome stalling. Additionally, numerous bacteria possess an EF-P...
6.
Mertinkus K, Oxenfarth A, Richter C, Wacker A, Mata C, Carazo J, et al.
J Am Chem Soc
. 2024 Oct;
146(44):30139-30154.
PMID: 39442924
Throughout the family of coronaviruses, structured RNA elements within the 5' region of the genome are highly conserved. The fifth stem-loop element from SARS-CoV-2 (5_SL5) represents an example of an...
7.
Tants J, Schlundt A
Biosci Rep
. 2024 Oct;
44(10).
PMID: 39364891
Regulatory RNA elements fulfill functions such as translational regulation, control of transcript levels, and regulation of viral genome replication. Trans-acting factors (i.e., RNA-binding proteins) bind the so-called cis elements and...
8.
Oberstrass L, Tants J, Lichtenthaeler C, Ali S, Koch L, Mathews D, et al.
Angew Chem Int Ed Engl
. 2024 Sep;
63(50):e202412596.
PMID: 39344866
The cellular levels of mRNAs are controlled post-transcriptionally by cis-regulatory elements located in the 3'-untranslated region. These linear or structured elements are recognized by RNA-binding proteins (RBPs) to modulate mRNA...
9.
Tants J, Oberstrass L, Weigand J, Schlundt A
Nucleic Acids Res
. 2024 Jul;
52(16):9838-9853.
PMID: 38953172
Zinc finger (ZnF) domains appear in a pool of structural contexts and despite their small size achieve varying target specificities, covering single-stranded and double-stranded DNA and RNA as well as...
10.
von Ehr J, Oberstrass L, Yazgan E, Schnaubelt L, Blumel N, McNicoll F, et al.
J Biol Chem
. 2024 Jun;
300(7):107457.
PMID: 38866324
AT-rich interacting domain (ARID)-containing proteins, Arids, are a heterogeneous DNA-binding protein family involved in transcription regulation and chromatin processing. For the member Arid5a, no exact DNA-binding preference has been experimentally...