Andreas Lennartsson
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Explore the profile of Andreas Lennartsson including associated specialties, affiliations and a list of published articles.
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4296
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Recent Articles
1.
Rombaut D, Sandmann S, Tekath T, Crouch S, de Graaf A, Smith A, et al.
Hemasphere
. 2025 Jan;
9(1):e70073.
PMID: 39850648
Lower risk (LR) myelodysplastic syndromes (MDS) are heterogeneous hematopoietic stem and progenitor disorders caused by the accumulation of somatic mutations in various genes including epigenetic regulators that may produce convergent...
2.
Miliara S, Cozzi E, Zhong X, Chan I, Ekwall K, Lehmann S, et al.
Leukemia
. 2023 Nov;
38(3):663-666.
PMID: 38036629
No abstract available.
3.
Palau A, Segerberg F, Lidschreiber M, Lidschreiber K, Naughton A, Needhamsen M, et al.
Leukemia
. 2023 Jul;
37(9):1830-1841.
PMID: 37495775
Isocitrate dehydrogenase (IDH) mutations are found in 20% of acute myeloid leukemia (AML) patients. However, only 30-40% of the patients respond to IDH inhibitors (IDHi). We aimed to identify a...
4.
Marakulina D, Vorontsov I, Kulakovskiy I, Lennartsson A, Drablos F, Medvedeva Y
Nucleic Acids Res
. 2022 Nov;
51(D1):D564-D570.
PMID: 36350659
We present an update of EpiFactors, a manually curated database providing information about epigenetic regulators, their complexes, targets, and products which is openly accessible at http://epifactors.autosome.org. An updated version of...
5.
Romanova E, Zubritskiy A, Lioznova A, Ogunleye A, Golotin V, Guts A, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232714
Acute myeloid leukemia (AML) is a rapidly progressing heterogeneous disease with a high mortality rate, which is characterized by hyperproliferation of atypical immature myeloid cells. The number of AML patients...
6.
Kalushkova A, Nylund P, Parraga A, Lennartsson A, Jernberg-Wiklund H
Epigenomes
. 2021 Dec;
5(4).
PMID: 34968247
Aberrant DNA methylation, dysregulation of chromatin-modifying enzymes, and microRNAs (miRNAs) play a crucial role in haematological malignancies. These epimutations, with an impact on chromatin accessibility and transcriptional output, are often...
7.
Stiernborg M, Efstathopoulos P, Lennartsson A, Lavebratt C, Mathe A
Acta Neuropsychiatr
. 2021 Oct;
34(2):86-92.
PMID: 34666848
Since the NAD+-dependent histone deacetylases sirtuin-1 (SIRT1) and sirtuin-2 (SIRT2) are critically involved in epigenetics, endocrinology and immunology and affect the longevity in model organisms, we investigated their expression in...
8.
Dong W, Prasad P, Lennartsson A, Ekwall K
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33670267
The Helicase-related protein 3 (Hrp3), an ATP-dependent chromatin remodeling enzyme from the CHD family, is crucial for maintaining global nucleosome occupancy in (. Although the ATPase domain of Hrp3 is...
9.
Mareschal S, Palau A, Lindberg J, Ruminy P, Nilsson C, Bengtzen S, et al.
Blood Adv
. 2021 Feb;
5(4):1003-1016.
PMID: 33591326
Although copy number alterations (CNAs) and translocations constitute the backbone of the diagnosis and prognostication of acute myeloid leukemia (AML), techniques used for their assessment in routine diagnostics have not...
10.
Ramilowski J, Yip C, Agrawal S, Chang J, Ciani Y, Kulakovskiy I, et al.
Genome Res
. 2020 Jul;
30(7):1060-1072.
PMID: 32718982
Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down...